通过皮肤点刺试验对鼻支气管过敏患者的皮肤对各种过敏原的敏感性进行研究。
A study of skin sensitivity to various allergens by skin prick test in patients of nasobronchial allergy.
作者信息
Prasad R, Verma S K, Dua R, Kant S, Kushwaha R A S, Agarwal S P
机构信息
Department of Pulmonary Medicine, K.G. Medical University, Lucknow, UP, India.
出版信息
Lung India. 2009 Jul;26(3):70-3. doi: 10.4103/0970-2113.53228.
OBJECTIVE
To study skin sensitivity to various allergens in patients of nasobronchial allergy.
MATERIALS AND METHODS
2880 skin prick tests with 60 allergens were performed in 48 patients of nasobronchial allergy.
RESULTS
Most common offending allergens were insects (21.2%), followed by dusts (12.0%), pollens (7.8%), animal dander (3.1%), and fungi (1.3%). The common insect antigen were locust female (33.3%) followed by locust male (25%), grasshopper (20.8%), cricket (16.7%), cockroach female (16.7%) and cockroach male (14.6%). Common dust allergens were house dust, wheat dust, cotton mill and paper dust. Among pollens, Amaranthus spinosus, Argemone mexicana, Adhatoda vasica, Ailanthus and Cannabis were found to be common allergens. In animal danders common offending allergens were cow dander and dog dander. Among fungi Aspergillus fumigatus, Aspergillus flavus, Alternaria teneis and Fusarium sodani were common allergens. Patients of bronchial asthma had associated allergic rhinitis in 80% cases.
CONCLUSION
Common allergens in patients of nasobronchial allergy were identified. The data may prove useful in of allergen avoidance and immunotherapy in these patients.
目的
研究鼻支气管过敏患者对各种变应原的皮肤敏感性。
材料与方法
对48例鼻支气管过敏患者进行了60种变应原的2880次皮肤点刺试验。
结果
最常见的致病变应原是昆虫（21.2%），其次是灰尘（12.0%）、花粉（7.8%）、动物皮屑（3.1%）和真菌（1.3%）。常见的昆虫抗原是雌性蝗虫（33.3%），其次是雄性蝗虫（25%）、蚱蜢（20.8%）、蟋蟀（16.7%）、雌性蟑螂（16.7%）和雄性蟑螂（14.6%）。常见的灰尘变应原是屋尘、小麦尘、棉尘和纸尘。在花粉中，刺苋、蓟罂粟、鸭嘴花、臭椿和大麻被发现是常见变应原。在动物皮屑中，常见的致病变应原是牛毛和狗毛。在真菌中，烟曲霉、黄曲霉、链格孢和茄病镰刀菌是常见变应原。80%的支气管哮喘患者伴有过敏性鼻炎。
结论
确定了鼻支气管过敏患者的常见变应原。这些数据可能对这些患者的变应原回避和免疫治疗有用。
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