Jibiki I, Kurokawa K, Yamaguchi N
Department of Neuropsychiatry, Kanazawa University School of Medicine, Japan.
Eur Neurol. 1991;31(3):149-51. doi: 10.1159/000116665.
N-isopropyl-[123I]-p-iodoamphetamine (123I-IMP) single-photon emission computed tomography (SPECT) brain imaging was repeatedly performed in a 68-year-old man with the interval form of CO poisoning. The initial SPECT under an akinetic-mutism state following the interval period of about 18 days showed high-grade hypoperfusion images in diffuse regions extending to both the gray and white matter in the cerebral cortex. The second SPECT examination performed 328 days after the acute poisoning showed that the diffuse hypoperfusion images had become lighter but remained to a degree consistent with the delay in the recovery from the akinetic-mutism state. The high utility of SPECT brain imaging in determining the diagnosis or prognosis of CO poisoning was discussed in comparison with X-ray or magnetic-resonance imaging findings.
对一名68岁患有间发性一氧化碳中毒的男性患者反复进行了N-异丙基-[123I]-对碘安非他明（123I-IMP）单光子发射计算机断层扫描（SPECT）脑成像检查。在间隔约18天的无动性缄默状态下进行的首次SPECT显示，弥漫性区域存在高度灌注不足图像，延伸至大脑皮质的灰质和白质。急性中毒328天后进行的第二次SPECT检查显示，弥漫性灌注不足图像有所减轻，但仍与无动性缄默状态恢复延迟的程度相符。与X射线或磁共振成像结果相比，讨论了SPECT脑成像在确定一氧化碳中毒诊断或预后方面的高实用性。
