Baraki H, Feltgen N, Roider J, Hoerauf H, Klatt C
Augenklinik, Universitätsmedizin Göttingen, Robert-Koch-Strasse 40, 37075, Göttingen, Deutschland.
Ophthalmologe. 2010 May;107(5):479-92; quiz 493. doi: 10.1007/s00347-010-2154-3.
In the acute stage central serous chorioretinopathy (CSC) is characterized by serous retinal detachment. Monofocal or multifocal structural changes of the pigment epithelium layer are common. Unilateral blurred vision is the major clinical symptom. The pathogenesis is unclear but corticosteroids and stress may trigger the disease. Normal vision often returns spontaneously within a few months. Therapeutic options are at a low evidence level. Carbonic anhydrase, mild laser photocoagulation, selective retinal therapy, photodynamic therapy and the intravitreal injection of bevacizumab have been reported. The authors suggest a treatment strategy on the basis of the available data.
在急性期，中心性浆液性脉络膜视网膜病变（CSC）的特征为浆液性视网膜脱离。色素上皮层的单灶或多灶性结构改变较为常见。单侧视力模糊是主要临床症状。其发病机制尚不清楚，但皮质类固醇和压力可能引发该病。正常视力通常在数月内自发恢复。治疗选择的证据水平较低。已有报道采用碳酸酐酶、轻度激光光凝、选择性视网膜治疗、光动力疗法以及玻璃体腔内注射贝伐单抗。作者根据现有数据提出了一种治疗策略。
