Department of Neurology, Kirikkale University Faculty of Medicine, Kirikkale, Turkey.
Pain Med. 2010 Jul;11(7):1107-14. doi: 10.1111/j.1526-4637.2010.00837.x. Epub 2010 Apr 26.
The Self-Administered Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) is a 7-item self-report scale developed to identify pain of predominantly neuropathic origin. The aim of this study was to develop a Turkish version of the S-LANSS and to test its validity and reliability in chronic pain patients.
We enrolled 244 chronic pain patients treated at the Neurology Department. The original version of the S-LANSS was translated into Turkish by standard procedures. An independent clinician determined the pain type (neuropathic vs nociceptive). The reliability (internal consistency and test-retest reliability) and validity (agreement with the reference diagnosis and sensitivity, specificity, and positive and negative predictive values) were determined.
Two-hundred and forty-four patients with chronic pain (167 women, 43.1 +/- 11.4 years), 137, neuropathic pain and 107, nociceptive pain, were asked to complete the S-LANSS twice. Cronbach's alpha-coefficient was 0.74 for the test and 0.73 for the retest. Total S-LANSS scores for subjects did not significantly differ between applications (P = 0.46). Correlation coefficient was r: 0.97 (P < 0.01), which is fairly high for a self-assessment tool. Compared with the clinical assessment, the sensitivity and specificity of the S-LANSS were 72.3% (95% CI, 64.0-79.6%) and 80.4% (95% CI, 71.6-87.4%), respectively, for both the test and retest. The sensitivity and specificity of the Turkish S-LANSS were similar to those determined in the original validation study.
This study reports the first validation of a translated version of the S-LANNS into another language. The results suggest that the Turkish version of S-LANSS is a reliable and valid differential diagnostic measure of neuropathic pain in chronic pain patients.
自我管理的利兹评估神经病理性症状和体征（S-LANSS）是一种 7 项自我报告量表，用于识别主要为神经病理性起源的疼痛。本研究的目的是开发 S-LANSS 的土耳其语版本，并在慢性疼痛患者中测试其有效性和可靠性。
我们招募了 244 名在神经科接受治疗的慢性疼痛患者。S-LANSS 的原始版本通过标准程序翻译成土耳其语。一位独立的临床医生确定疼痛类型（神经病理性与伤害感受性）。确定了可靠性（内部一致性和重测信度）和有效性（与参考诊断的一致性以及敏感性、特异性、阳性和阴性预测值）。
244 名慢性疼痛患者（167 名女性，43.1 +/- 11.4 岁），137 名神经病理性疼痛和 107 名伤害感受性疼痛，被要求两次完成 S-LANSS。测试时的克朗巴赫 α 系数为 0.74，重测时为 0.73。两次应用时，受试者的 S-LANSS 总分无显著差异（P = 0.46）。相关系数 r 为 0.97（P < 0.01），对于自我评估工具来说相当高。与临床评估相比，S-LANSS 的敏感性和特异性在测试和重测时分别为 72.3%（95%CI，64.0-79.6%）和 80.4%（95%CI，71.6-87.4%）。土耳其 S-LANSS 的敏感性和特异性与原始验证研究中确定的相似。
本研究报告了将 S-LANSS 翻译成另一种语言的首次验证。结果表明，土耳其语版 S-LANSS 是慢性疼痛患者中神经病理性疼痛的可靠和有效鉴别诊断工具。
