精神病性抑郁症中针对单纯疱疹病毒的抗体介导免疫和细胞介导免疫
Antibody and cell-mediated immunity to herpes simplex virus in psychotic depression.
作者信息
Cappel R, Gregoire F, Thiry L, Sprecher S
出版信息
J Clin Psychiatry. 1978 Mar;39(3):266-8.
PMID:204625
Abstract
The incidence and antibody titers to herpes simplex virus (HSV) were found significantly higher in patients with psychotic depression as compared to normal controls. Furthermore, the cell-mediated immunity (CMI) to HSV in psychotic depression was similar to that observed after acute HSV infection or recurrence. The results suggest therefore an association between HSV infection and psychotic depression.
摘要
与正常对照组相比，发现患有精神病性抑郁症的患者中单纯疱疹病毒（HSV）的发病率和抗体滴度显著更高。此外，精神病性抑郁症患者对HSV的细胞介导免疫（CMI）与急性HSV感染或复发后观察到的情况相似。因此，结果提示HSV感染与精神病性抑郁症之间存在关联。
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