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氧化铁纳米颗粒对金黄色葡萄球菌的杀菌作用。

Bactericidal effect of iron oxide nanoparticles on Staphylococcus aureus.

机构信息

Department of Physics, Brown University, Providence, Rhode Island, USA.

出版信息

Int J Nanomedicine. 2010 Apr 15;5:277-83. doi: 10.2147/ijn.s9220.

Abstract

In order to study the effects of iron oxide (IO) nanoparticles on Staphylococcus aureus, IO nanoparticles were synthesized via a novel matrix-mediated method using polyvinyl alcohol (PVA). The IO nanoparticles were characterized by transmission electron microscopy and dynamic light scattering. Further, S. aureus were grown in the presence of three different IO nanoparticle concentrations for four, 12, and 24 hours. Live/dead assays were performed and the results provide evidence that IO/PVA nanoparticles inhibited S. aureus growth at the highest concentration (3 mg/mL) at all time points.

摘要

为了研究氧化铁(IO)纳米粒子对金黄色葡萄球菌的影响,通过使用聚乙烯醇(PVA)的新型基质介导方法合成了 IO 纳米粒子。通过透射电子显微镜和动态光散射对 IO 纳米粒子进行了表征。进一步,在三种不同 IO 纳米粒子浓度下,将金黄色葡萄球菌生长 4、12 和 24 小时。进行了死活检测,结果表明,在所有时间点,IO/PVA 纳米粒子在最高浓度(3mg/ml)下均抑制了金黄色葡萄球菌的生长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62fb/2865022/6e76aa39d127/ijn-5-277f1.jpg

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