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药物不良反应与药物信息需求

Adverse drug effects and the need for drug information.

作者信息

Enlund H, Vainio K, Wallenius S, Poston J W

机构信息

Department of Social Pharmacy, University of Kuopio, Finland.

出版信息

Med Care. 1991 Jun;29(6):558-64. doi: 10.1097/00005650-199106000-00014.

DOI:10.1097/00005650-199106000-00014
PMID:2046409
Abstract

The information needs of a group of patients taking antihypertensive medication were assessed with special emphasis on the influence of perceived symptoms of high blood pressure and adverse drug effects. All patients of a hypertension clinic currently on antihypertensive medication were included in the study. The response rate to the questionnaire was 85%. Of the 623 patients included, only 31% expressed satisfaction with the amount of information received on adverse effects of their antihypertensive drugs. Patients younger than 50 years explicitly expressed a need for information more often than those older than 64. There were no differences in the expressed information needs between men and women. The reported experience of symptoms related to high blood pressure and adverse drug effects was more common among younger patients than among the elderly. Of those who experienced both adverse drug effects and symptoms, 57% expressed a need for more information, whereas only 30% of those who had no such experiences expressed a need for more information on adverse drug effects. It was concluded that there is a substantial need for more information on adverse drug effects, especially among those who have experienced adverse drug effects or some symptoms of hypertension.

摘要

对一组服用抗高血压药物的患者的信息需求进行了评估,特别强调了高血压感知症状和药物不良反应的影响。高血压诊所目前正在服用抗高血压药物的所有患者都纳入了该研究。问卷的回复率为85%。在纳入的623名患者中,只有31%对所获得的关于其抗高血压药物不良反应的信息量表示满意。50岁以下的患者比64岁以上的患者更明确地表示需要信息。男性和女性在表达的信息需求方面没有差异。报告的与高血压和药物不良反应相关的症状经历在年轻患者中比在老年患者中更常见。在经历了药物不良反应和症状的患者中,57%表示需要更多信息,而在没有此类经历的患者中,只有30%表示需要更多关于药物不良反应的信息。得出的结论是,非常需要更多关于药物不良反应的信息,特别是在那些经历过药物不良反应或一些高血压症状的患者中。

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