Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, China.
Int J Dermatol. 2010 Feb;49(2):141-5. doi: 10.1111/j.1365-4632.2009.04178.x.
This study investigates four special cases associated with Malassezia.
The special clinical manifestations, mycologic examination, and treatment were reviewed intensively.
An abundance of Malassezia hyphae were found in the scales of the three cases presenting with erythematous patches and in another case presenting with dystrophic nails. Malassezia globosa was identified and confirmed by culture. Antifungal agents were effective in the treatment of all cases.
Malassezia is an opportunistic fungus that may induce dermatosis other than classical pityriasis versicolor. Hyphae from the lesions may be induced by a change in the microenvironment of the fungus caused by the local application of corticosteroids.
本研究调查了与糠秕马拉色菌相关的四种特殊情况。
我们深入回顾了这些特殊病例的临床表现、真菌学检查和治疗方法。
在三例红斑斑块和一例营养不良性指甲病变的患者的鳞屑中，发现了大量糠秕马拉色菌的菌丝。通过培养鉴定并确认了球形马拉色菌。所有病例的抗真菌药物治疗均有效。
糠秕马拉色菌是一种机会性真菌，它可能会引起除经典花斑癣以外的其他皮肤疾病。病变处的菌丝可能是由于局部应用皮质类固醇引起真菌微环境改变而诱导产生的。
