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治疗危重病患者的胃排空延迟:甲氧氯普胺、红霉素和床边(cortrak)鼻肠管放置。

Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement.

机构信息

Department of Nutrition and Dietetics, Frenchay Hospital, Bristol, UK.

出版信息

JPEN J Parenter Enteral Nutr. 2010 May-Jun;34(3):289-94. doi: 10.1177/0148607110362533.

DOI:10.1177/0148607110362533
PMID:20467010
Abstract

BACKGROUND

We describe experience using the Cortrak nasointestinal feeding tube and prokinetics in critically ill patients with delayed gastric emptying.

METHODS

Patient cohorts fed via a Cortrak electromagnetically guided nasointestinal tube (EGNT) or 14 French-gauge nasogastric tube plus prokinetics were retrospectively compared.

RESULTS

Of 69 EGNT placements in 62 patients, 87% reached the small intestine. The median percentage of the enteral nutrition goal increased from 19% pre-EGNT to 80%-100% between days 1 and 10 post-insertion and was greater than in 58 patients prescribed metoclopramide (40%-87%: days 1-2, 5-7, P < or = .018) or 38 patients prescribed erythromycin (48%-98%; days 1 and 5, P < .0084). Up to day 10, the cumulative feeding days lost were lower for EGNT (1.06) than for metoclopramide (2.6, P < .02) or erythromycin (3.1, P < .02). The EGNT group had a lower use of prokinetics and lower treatment cost.

CONCLUSION

Most bedside EGNT placements succeed and, compared to nasogastric feeding plus prokinetics, increase enteral nutrition delivery and reduce both cumulative feeding days lost and prokinetic use.

摘要

背景

我们描述了在患有胃排空延迟的危重症患者中使用 Cortrak 经鼻肠喂养管和促动力药物的经验。

方法

回顾性比较了经 Cortrak 电磁引导经鼻肠喂养管(EGNT)或 14 号鼻胃管加促动力药物喂养的患者队列。

结果

在 62 例患者的 69 次 EGNT 置管中,87%的管到达小肠。肠内营养目标的中位数百分比从 EGNT 前的 19%增加到插入后第 1 天至第 10 天的 80%-100%,并且大于 58 例接受甲氧氯普胺(40%-87%:第 1-2 天、第 5-7 天,P≤.018)或 38 例接受红霉素(48%-98%;第 1 天和第 5 天,P<.0084)治疗的患者。在第 10 天之前,EGNT 组的累计失喂天数(1.06)低于甲氧氯普胺组(2.6,P<.02)或红霉素组(3.1,P<.02)。EGNT 组使用促动力药物的频率更低,治疗费用也更低。

结论

大多数床边 EGNT 置管都成功了,与鼻胃管喂养加促动力药物相比,增加了肠内营养的输送,减少了累计失喂天数和促动力药物的使用。

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