高比例的混合物种疟原虫感染在印度被 PCR 诊断检测揭示。
High proportion of mixed-species Plasmodium infections in India revealed by PCR diagnostic assay.
机构信息
National Institute of Malaria Research, Dwarka, New Delhi, India.
出版信息
Trop Med Int Health. 2010 Jul;15(7):819-24. doi: 10.1111/j.1365-3156.2010.02549.x. Epub 2010 May 14.
Abstract
Accurate diagnosis is the key to effective treatment and control of malaria. We screened 180 microscopically diagnosed Indian malaria-positive blood samples for pure and mixed infections by Plasmodium falciparum and Plasmodium vivax. An unusually high proportion of mixed infections was detected, signifying the sensitivity of PCR assay over traditional microscopic diagnosis.
摘要
准确的诊断是疟疾有效治疗和控制的关键。我们对 180 份经显微镜诊断为印度疟原虫阳性的血液样本进行了纯感染和混合感染的筛选，包括恶性疟原虫和间日疟原虫。结果发现混合感染的比例非常高，这表明 PCR 检测比传统的显微镜诊断更灵敏。
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