Department of Physics, Science Faculty, Atatürk University, Erzurum, Turkey.
J Xray Sci Technol. 2010;18(2):111-20. doi: 10.3233/XST-2010-0247.
The present study investigated the trace element contents in the blood sera of type II diabetic patients with and without complication as compared to non-diabetic healthy controls. The elements Na, Mg, Al, Si, P, S, Cl, K, Ca, Cr, Mn, Fe, Ni, Cu, Zn, Se, Mo, Cd, Hg and Pb were determined by wavelength dispersive x-ray fluorescence spectrometry. Blood serum levels of some trace elements in patients with type II diabetes mellitus showed significant deviations from healthy controls. Mean Ca, Cu and Se (p< 0.05) concentrations (%) in both diabetic patients with and without complication were significantly lower than those in healthy controls. When compared with non-diabetic control group, the Mg concentrations of patients without complication were decreasing while Mg levels of patients with at least one complication were increasing (p< 0.05). Si levels were significantly higher both in diabetic patients with complication and without complication than healthy controls (p< 0.05). K and Hg levels of diabetic patients with at least one complication have significantly deviated from both healthy controls and patients without complication (p< 0.05). There were no significant differences between control group and diabetic patients concerning height, age, weight and body mass index (p> 0.05).
本研究调查了 II 型糖尿病患者（有并发症和无并发症者）与非糖尿病健康对照者血清中微量元素的含量。采用波长色散 X 射线荧光光谱法测定了血清中 Na、Mg、Al、Si、P、S、Cl、K、Ca、Cr、Mn、Fe、Ni、Cu、Zn、Se、Mo、Cd、Hg 和 Pb 等元素。与健康对照组相比，II 型糖尿病患者的一些微量元素的血清水平存在显著偏差。有并发症和无并发症的糖尿病患者的 Ca、Cu 和 Se 平均浓度（%）（p<0.05）显著低于健康对照组。与非糖尿病对照组相比，无并发症患者的 Mg 浓度降低，而至少有一个并发症的患者的 Mg 水平升高（p<0.05）。合并症患者和无合并症患者的 Si 水平均显著高于健康对照组（p<0.05）。至少有一个并发症的糖尿病患者的 K 和 Hg 水平与健康对照组和无并发症患者均有显著差异（p<0.05）。对照组和糖尿病患者在身高、年龄、体重和体重指数方面无显著差异（p>0.05）。
