Howard Hughes Medical Institute, Department of Pharmacology, University of Washington, School of Medicine, Seattle, Washington, USA.
Nat Struct Mol Biol. 2010 Jun;17(6):653-8. doi: 10.1038/nsmb.1843. Epub 2010 May 23.
A cell's response to its environment is often determined by signaling through the actions of enzyme cascades. The ability to organize these enzymes into multiprotein complexes allows for a high degree of fidelity, efficiency and spatial precision in signaling responses.
细胞对其环境的反应通常是通过酶级联反应的信号转导来决定的。将这些酶组织成多蛋白复合物的能力使得信号转导反应具有高度的保真度、效率和空间精度。