Kim Geun Woo, Doo Seung Whan, Yang Won Jae, Song Yun Seob
Department of Urology, Soonchunhyang University College of Medicine, Seoul, Korea.
Korean J Urol. 2010 May;51(5):344-7. doi: 10.4111/kju.2010.51.5.344. Epub 2010 May 19.
We investigated the effects of obesity on prostate volume (PV) and lower urinary tract symptoms (LUTS) in Korean men.
From December 2007 to 2009, a total of 10,383 ostensibly healthy Korean men aged >/=50 years visited our health promotion center for a routine check-up. Among them, 872 men who wanted a prostate evaluation were enrolled in this study. All men underwent detailed clinical evaluations with the International Prostate Symptom Score (IPSS) questionnaire. Anthropometric measurements, including height, weight, and waist and hip circumferences, were determined. A blood sample was obtained for serum prostate-specific antigen (PSA) measurement. Thereafter, a digital rectal examination and transrectal ultrasound were performed.
In total, 465 men with moderate to severe LUTS (IPSS>/=8 points) were included in this prospective study. The participants' mean age was 57.2 years. Multivariate analysis demonstrated that only waist circumference was a significant factor in predicting PV besides age and serum PSA. The univariate analysis showed no statistically significant relations between any of the obesity-related parameters and LUTS. The PV was also not correlated with LUTS.
Central obesity is the more important predictor of PV than overall obesity. There are no significant relations between obesity-related parameters and LUTS.
我们研究了肥胖对韩国男性前列腺体积（PV）和下尿路症状（LUTS）的影响。
2007年12月至2009年，共有10383名表面健康、年龄≥50岁的韩国男性到我们的健康促进中心进行例行体检。其中，872名希望进行前列腺评估的男性被纳入本研究。所有男性均使用国际前列腺症状评分（IPSS）问卷进行详细的临床评估。测定了身高、体重、腰围和臀围等人体测量指标。采集血液样本进行血清前列腺特异性抗原（PSA）检测。此后，进行了直肠指检和经直肠超声检查。
本前瞻性研究共纳入465名中重度LUTS（IPSS≥8分）男性。参与者的平均年龄为57.2岁。多变量分析表明，除年龄和血清PSA外,只有腰围是预测PV的重要因素。单变量分析显示，任何肥胖相关参数与LUTS之间均无统计学意义上的关联。PV与LUTS也无相关性。
中心性肥胖比全身性肥胖更能预测PV。肥胖相关参数与LUTS之间无显著关联。
