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The Mohawk homeobox gene is a critical regulator of tendon differentiation.
Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10538-42. doi: 10.1073/pnas.1000525107. Epub 2010 May 24.
2
The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis.
Mol Cell Biol. 2010 Oct;30(20):4797-807. doi: 10.1128/MCB.00207-10. Epub 2010 Aug 9.
3
The Mohawk homeobox transcription factor regulates the differentiation of tendons and volar plates.
J Orthop Sci. 2014 Jan;19(1):172-80. doi: 10.1007/s00776-013-0485-z. Epub 2013 Oct 29.
5
The transcription factor mohawk homeobox regulates homeostasis of the periodontal ligament.
Development. 2017 Jan 15;144(2):313-320. doi: 10.1242/dev.135798. Epub 2016 Dec 19.
6
Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization.
J Orthop Res. 2013 Sep;31(9):1475-83. doi: 10.1002/jor.22382. Epub 2013 May 7.
8
Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon.
Mol Cell Biol. 2016 Mar 31;36(8):1297-309. doi: 10.1128/MCB.00950-15. Print 2016 Apr.
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Establishment of a human pluripotent stem cell-derived MKX-td Tomato reporter system.
Stem Cell Res Ther. 2022 Nov 12;13(1):515. doi: 10.1186/s13287-022-03203-5.
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Gene targeting of the transcription factor Mohawk in rats causes heterotopic ossification of Achilles tendon via failed tenogenesis.
Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7840-5. doi: 10.1073/pnas.1522054113. Epub 2016 Jul 1.

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Matrix stiffness regulates Mkx expression in rat tenocyte through TRPM7.
Biochem Biophys Rep. 2025 Jul 23;43:102178. doi: 10.1016/j.bbrep.2025.102178. eCollection 2025 Sep.
2
Transcription factor Mohawk regulates tendon/ligament development: A narrative review.
Medicine (Baltimore). 2025 Jul 25;104(30):e43044. doi: 10.1097/MD.0000000000043044.
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State-of the-art and future perspective in co-culture systems for tendon engineering.
Biomater Biosyst. 2025 Mar 5;17:100110. doi: 10.1016/j.bbiosy.2025.100110. eCollection 2025 Mar.
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Molecular dissection of tendon development and healing: Insights into tenogenic phenotypes and functions.
J Biol Chem. 2025 Apr;301(4):108353. doi: 10.1016/j.jbc.2025.108353. Epub 2025 Feb 25.
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Impact of mechanotransduction on gene expression changes in periodontal ligament during orthodontic tooth movement.
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Mechanisms and new advances in the efficacy of plant active ingredients in tendon-bone healing.
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IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia.
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4
Dynamic gene expression of Lin-28 during embryonic development in mouse and chicken.
Gene Expr Patterns. 2008 Feb;8(3):155-60. doi: 10.1016/j.gep.2007.11.001. Epub 2007 Nov 17.
5
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche.
Nat Med. 2007 Oct;13(10):1219-27. doi: 10.1038/nm1630. Epub 2007 Sep 9.
6
Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons.
Development. 2007 Jul;134(14):2697-708. doi: 10.1242/dev.001933. Epub 2007 Jun 13.
7
Scleraxis and NFATc regulate the expression of the pro-alpha1(I) collagen gene in tendon fibroblasts.
J Biol Chem. 2007 Jun 15;282(24):17665-75. doi: 10.1074/jbc.M610113200. Epub 2007 Apr 12.
8
TALE-family homeodomain proteins regulate endodermal sonic hedgehog expression and pattern the anterior endoderm.
Dev Biol. 2007 Apr 1;304(1):221-31. doi: 10.1016/j.ydbio.2006.12.024. Epub 2006 Dec 15.
9
Biology of tendon injury: healing, modeling and remodeling.
J Musculoskelet Neuronal Interact. 2006 Apr-Jun;6(2):181-90.
10
Irxl1, a divergent Iroquois homeobox family transcription factor gene.
Gene Expr Patterns. 2007 Jan;7(1-2):51-6. doi: 10.1016/j.modgep.2006.05.007. Epub 2006 May 26.

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