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饮酒与胃食管反流病有关吗?

Is alcohol consumption associated with gastroesophageal reflux disease?

机构信息

Department of Gastroenterology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.

出版信息

J Zhejiang Univ Sci B. 2010 Jun;11(6):423-8. doi: 10.1631/jzus.B1000013.

DOI:10.1631/jzus.B1000013
PMID:20506572
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2880354/
Abstract

Gastroesophageal reflux disease (GERD) is one of the most common disorders with an increasing incidence and prevalence. Alcohol consumption may be a risk factor for GERD; however, the relationship remains to be fully elucidated. The results of different studies are diverse and contradictory. Systematic investigations concerning this matter are inappropriate and further well-designed prospective studies are needed to clarify the effect of alcohol on GERD.

摘要

胃食管反流病(GERD)是一种最常见的疾病,发病率和患病率呈上升趋势。饮酒可能是 GERD 的一个危险因素,但两者的关系仍有待充分阐明。不同研究的结果存在差异和矛盾。因此,针对这一问题进行系统研究是不合适的,需要进一步设计良好的前瞻性研究来阐明酒精对 GERD 的影响。

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本文引用的文献

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Am J Med Sci. 2009 Aug;338(2):89-95. doi: 10.1097/MAJ.0b013e3181ad584a.
2
Comparison of risk factors and clinical responses to proton pump inhibitors in patients with erosive oesophagitis and non-erosive reflux disease.比较质子泵抑制剂在糜烂性食管炎和非糜烂性反流病患者中的危险因素和临床反应。
Aliment Pharmacol Ther. 2009 Jul 1;30(2):154-64. doi: 10.1111/j.1365-2036.2009.04021.x. Epub 2009 Apr 15.
3
The association between alcohol and reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma.酒精与反流性食管炎、巴雷特食管和食管腺癌之间的关联。
Gastroenterology. 2009 Mar;136(3):799-805. doi: 10.1053/j.gastro.2008.12.005. Epub 2008 Dec 3.
4
Alcohol consumption is associated with an increased risk of erosive esophagitis and Barrett's epithelium in Japanese men.在日本男性中,饮酒与糜烂性食管炎和巴雷特食管上皮化生风险增加有关。
BMC Gastroenterol. 2008 Dec 11;8:58. doi: 10.1186/1471-230X-8-58.
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The additive effect of ethanol and extract of cigarette smoke on rabbit esophagus epithelium.乙醇与香烟烟雾提取物对兔食管上皮的叠加效应。
J Gastroenterol Hepatol. 2009 Feb;24(2):316-21. doi: 10.1111/j.1440-1746.2008.05634.x. Epub 2008 Nov 20.
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Chronic alcoholism and esophageal motor activity: a 24-h ambulatory manometry study.慢性酒精中毒与食管运动活性:一项24小时动态测压研究。
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Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data.《2001年全球和区域疾病负担及风险因素:对人群健康数据的系统分析》
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Aliment Pharmacol Ther. 2006 Jun 1;23(11):1581-6. doi: 10.1111/j.1365-2036.2006.02922.x.