Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
Jpn J Radiol. 2010 May;28(4):318-21. doi: 10.1007/s11604-010-0421-5. Epub 2010 May 29.
We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of hyperlipidemia who was suffering from an equilibrium disorder. Proton MRS revealed a high mobile lipids (Lip) peak between 0.9 and 1.4 ppm, which was compatible with histologically proven lipids in the tumor. No lactate peak was recognized. The creatine/phosphocreatine peak was low. Choline-containing compounds were increased. The N-acetylaspartate peak was absent, which indicated that the tumor is of nonneurogenic origin. Combined with the absence of the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma. These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma. However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma.
我们报告了一例 56 岁男性患有高脂血症病史的血管母细胞瘤质子磁共振波谱（MRS）检查病例，该患者患有平衡障碍。质子 MRS 显示在 0.9 到 1.4ppm 之间有一个高移动脂质（Lip）峰，与肿瘤中组织学证实的脂质相吻合。未识别到乳酸峰。肌酸/磷酸肌酸峰较低。含有胆碱的化合物增加。N-乙酰天冬氨酸峰缺失，这表明肿瘤不是神经源性的。结合磁共振成像上无坏死成分，质子 MRS 上的这个 Lip 峰可能是血管母细胞瘤的特征性模式。质子 MRS 的这些独特结果在颅内血管母细胞瘤的鉴别诊断中具有重要作用。然而，需要进一步的研究来确定血管母细胞瘤质子 MRS 的典型特征。
