Chen K, Khayam-Bashi H
Department of Laboratory Medicine, University of California School of Medicine, San Francisco General Hospital 94110.
J Anal Toxicol. 1991 Mar-Apr;15(2):82-5. doi: 10.1093/jat/15.2.82.
The gas chromatographic (GC) quantification of underivatized antiepileptic drugs such as carbamazepine, phenytoin, phenobarbital and primidone in fused-silica capillary columns was compared with that in packed columns. Excellent correlation was demonstrated between the two column methods by slopes of 0.99 to 1.05, by Y-intercepts of -0.47 to 0.28 and by r values of 0.996 and 0.997. In addition, some of the specimens from GC analysis by both column methods were compared with data obtained for these drugs as analyzed with the Abbott TDx system. Data obtained by both GC column methods showed excellent correlation.
将熔融石英毛细管柱中卡马西平、苯妥英、苯巴比妥和扑米酮等未衍生化抗癫痫药物的气相色谱（GC）定量方法与填充柱中的方法进行了比较。两种柱方法之间显示出极好的相关性，斜率为0.99至1.05，Y轴截距为-0.47至0.28，r值为0.996和0.997。此外，将两种柱方法进行GC分析得到的一些样本数据与使用雅培TDx系统分析这些药物所获得的数据进行了比较。两种GC柱方法获得的数据显示出极好的相关性。
