Mechanical Engineering, University of Michigan, Ann Arbor, MI, USA.
Lab Chip. 2010 Jun 21;10(12):1627-30. doi: 10.1039/c000863j. Epub 2010 Mar 25.
A direct fabrication method capable of producing fully-reversible, tunable nanochannel arrays, without the use of a molding step, is described. It is based on tunnel cracking of a readily-prepared brittle layer constrained between elastomeric substrates. The resulting nanochannels have adjustable cross-sections that can be reversibly opened, closed, widened and narrowed merely by applying and removing tensile strains to the substrate. This permits reversible trapping and release of nanoparticles, and easy priming or unclogging of the nanochannels for user-friendly and robust operations. The ease of fabrication and operation required to open and close the nanochannels is superior to previous approaches.
本文介绍了一种无需成型步骤即可直接制造完全可逆、可调谐纳米通道阵列的方法。该方法基于在弹性体基底之间的易于制备的脆性层的隧道开裂。所得到的纳米通道具有可调节的横截面，可以通过向基底施加和去除拉伸应变来可逆地打开、关闭、扩大和缩小。这允许纳米粒子的可逆捕获和释放，并且易于对纳米通道进行预处理或疏通，实现用户友好和稳健的操作。与以前的方法相比，这种制造和操作纳米通道的简便性具有优越性。
