Wolf R E
Arthritis Rheum. 1978 Mar;21(2):238-42. doi: 10.1002/art.1780210211.
The immune response of peripheral blood lymphocytes to measles, rubella, parainfluenza types 1, 2, and 3 RNA virus antigens and to varicella-zoster and herpes virus type 1 DNA virus antigens was evaluated in 14 patients with rheumatoid arthritis (RA) and 14 matched controls by assessing 3H-thymidine incorporation. The results demonstrated hyporesponsivenss of lymphocytes from RA patients to virus antigens and phytohemagglutinin (PHA), which did not appear to be nonspecific because of a lack of correlation between response to virus antigens and response to mitogens. The patterns of decreased responsiveness was suggestive of a relative restriction of hyporesponsiveness to RNA virus antigens.
通过评估³H-胸腺嘧啶核苷掺入情况，对14例类风湿性关节炎（RA）患者和14例配对对照者外周血淋巴细胞对麻疹、风疹、1型、2型和3型副流感RNA病毒抗原以及水痘-带状疱疹和1型疱疹DNA病毒抗原的免疫反应进行了评估。结果显示，RA患者淋巴细胞对病毒抗原和植物血凝素（PHA）反应低下，这似乎并非非特异性的，因为对病毒抗原的反应与对有丝分裂原的反应之间缺乏相关性。反应性降低的模式提示对RNA病毒抗原反应低下存在相对局限性。
