非动脉炎性前部缺血性视神经病变患者是否应给予类固醇治疗？
Should steroids be offered to patients with nonarteritic anterior ischemic optic neuropathy?
机构信息
Department of Ophthalmology, The Methodist Hospital, Houston, Texas, USA.
出版信息
J Neuroophthalmol. 2010 Jun;30(2):193-8. doi: 10.1097/WNO.0b013e3181e1f71f.
Abstract
The treatment of nonarteritic anterior optic neuropathy remains very limited and disappointing. Recent publications have suggested that oral steroids as well as intravitreal injections of steroids might be helpful to accelerate resolution of disc edema and improve visual outcome. However, the use of steroids to treat acute NAION remains largely debated.
摘要
非动脉炎性前部缺血性视神经病变的治疗仍然非常有限且令人失望。最近的出版物表明，口服类固醇以及玻璃体内注射类固醇可能有助于加速盘水肿的消退并改善视力预后。然而，使用类固醇治疗急性非动脉炎性前部缺血性视神经病变仍存在很大争议。
相似文献
1
Should steroids be offered to patients with nonarteritic anterior ischemic optic neuropathy?非动脉炎性前部缺血性视神经病变患者是否应给予类固醇治疗？
J Neuroophthalmol. 2010 Jun;30(2):193-8. doi: 10.1097/WNO.0b013e3181e1f71f.
2
Intravitreal triamcinolone for nonarteritic anterior ischemic optic neuropathy.玻璃体内注射曲安奈德治疗非动脉炎性前部缺血性视神经病变。
J Neuroophthalmol. 2008 Mar;28(1):77-8; author reply 78-9. doi: 10.1097/WNO.0b013e31816781f3.
3
Treatment of nonarteritic anterior ischemic optic neuropathy with intravitreal bevacizumab.玻璃体内注射贝伐单抗治疗非动脉炎性前部缺血性视神经病变
J Neuroophthalmol. 2007 Sep;27(3):238-40. doi: 10.1097/WNO.0b013e31814b273d.
4
Intravitreal triamcinolone or bevacizumab for nonarteritic anterior ischemic optic neuropathy: do they merit further study?玻璃体内注射曲安奈德或贝伐单抗治疗非动脉炎性前部缺血性视神经病变：它们值得进一步研究吗？
J Neuroophthalmol. 2007 Sep;27(3):161-3. doi: 10.1097/WNO.0b013e31814a61ae.
5
Surgery for nonarteritic anterior ischemic optic neuropathy.非动脉炎性前部缺血性视神经病变的手术治疗
Cochrane Database Syst Rev. 2012 Jan 18;1:CD001538. doi: 10.1002/14651858.CD001538.pub3.
6
Role of steroid therapy in nonarteritic anterior ischemic optic neuropathy.类固醇疗法在非动脉炎性前部缺血性视神经病变中的作用。
J Neuroophthalmol. 2010 Dec;30(4):388-9. doi: 10.1097/WNO.0b013e3181fab01b.
7
Aspirin therapy in nonarteritic anterior ischemic optic neuropathy.非动脉炎性前部缺血性视神经病变的阿司匹林治疗
Am J Ophthalmol. 1997 Feb;123(2):212-7. doi: 10.1016/s0002-9394(14)71038-4.
8
Surgery for nonarteritic anterior ischemic optic neuropathy.非动脉炎性前部缺血性视神经病变的手术治疗
Cochrane Database Syst Rev. 2015 Mar 12;2015(3):CD001538. doi: 10.1002/14651858.CD001538.pub4.
9
Surgery for nonarteritic anterior ischemic optic neuropathy.非动脉炎性前部缺血性视神经病变的手术治疗
Cochrane Database Syst Rev. 2000(2):CD001538. doi: 10.1002/14651858.CD001538.
10
Nonarteritic anterior ischemic optic neuropathy (NAION): a misnomer. Rearranging pieces of a puzzle to reveal a nonischemic papillopathy caused by vitreous separation.非动脉炎性前部缺血性视神经病变（NAION）：一个不恰当的名称。重新拼凑谜团碎片以揭示由玻璃体分离引起的非缺血性视乳头病变。
Ophthalmology. 2015 Mar;122(3):439-42. doi: 10.1016/j.ophtha.2014.11.011.
引用本文的文献
1
Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy Risk Among Patients With Diabetes.司美格鲁肽与糖尿病患者非动脉炎性前部缺血性视神经病变风险
JAMA Ophthalmol. 2025 May 1;143(5):400-407. doi: 10.1001/jamaophthalmol.2025.0349.
2
Clinical efficacy of dexamethasone parabulbar injection in patients with Nonarteritic anterior ischemic optic neuropathy.地塞米松球周注射治疗非动脉炎性前部缺血性视神经病变的临床疗效
Heliyon. 2024 May 8;10(10):e30578. doi: 10.1016/j.heliyon.2024.e30578. eCollection 2024 May 30.
3
Visual outcome of various dose of glucocorticoids treatment in nonarteritic anterior ischemic optic neuropathy- a retrospective analysis.各种剂量糖皮质激素治疗非动脉炎性前部缺血性视神经病变的视觉结果-回顾性分析。
BMC Ophthalmol. 2024 Mar 4;24(1):100. doi: 10.1186/s12886-024-03354-4.
4
Diversified Treatment Options of Adult Stem Cells for Optic Neuropathies.成人干细胞治疗视神经病变的多样化选择。
Cell Transplant. 2022 Jan-Dec;31:9636897221123512. doi: 10.1177/09636897221123512.
5
Non-arteritic anterior ischemic optic neuropathy with Cilioretinal artery occlusion: a case report.非动脉炎性前部缺血性视神经病变合并睫状视网膜动脉阻塞：一例报告。
BMC Ophthalmol. 2019 Nov 14;19(1):228. doi: 10.1186/s12886-019-1243-6.
6
Steroids in the treatment of nonarteritic anterior ischemic optic neuropathy: A PRISMA-compliant meta-analysis.类固醇治疗非动脉炎性前部缺血性视神经病变：一项遵循PRISMA标准的荟萃分析。
Medicine (Baltimore). 2019 Nov;98(46):e17861. doi: 10.1097/MD.0000000000017861.
7
Can subtenon methylprednisolone acetate be a choice for the acute non-arteritic ischemic optic neuropathy treatment?巩膜下注射醋酸甲基强的松龙能否作为急性非动脉炎性缺血性视神经病变的一种治疗选择？
Rom J Ophthalmol. 2016 Oct-Dec;60(4):275-278.
8
Nonarteritic anterior ischemic optic neuropathy: cause, effect, and management.非动脉炎性前部缺血性视神经病变：病因、影响及治疗
Eye Brain. 2017 Sep 27;9:23-28. doi: 10.2147/EB.S125311. eCollection 2017.
9
Risk of Nonarteritic Anterior Ischemic Optic Neuropathy Following End-Stage Renal Disease.终末期肾病后非动脉炎性前部缺血性视神经病变的风险
Medicine (Baltimore). 2016 Mar;95(12):e3174. doi: 10.1097/MD.0000000000003174.
10
Changes in macular layers in the early course of non-arteritic ischaemic optic neuropathy.非动脉炎性缺血性视神经病变早期黄斑层的变化
Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):561-7. doi: 10.1007/s00417-015-3066-3. Epub 2015 May 28.
本文引用的文献
1
Treatment of nonarteritic anterior ischemic optic neuropathy.非动脉炎性前部缺血性视神经病变的治疗。
Surv Ophthalmol. 2010 Jan-Feb;55(1):47-63. doi: 10.1016/j.survophthal.2009.06.008.
2
Translation of clinical studies to clinical practice: survey on the treatment of nonarteritic anterior ischemic optic neuropathy.临床研究向临床实践的转化：非动脉炎性前部缺血性视神经病变治疗的调查
Am J Ophthalmol. 2009 Nov;148(5):809. doi: 10.1016/j.ajo.2009.07.003.
3
The effect of an intravitreal triamcinolone acetonide injection for acute nonarteritic anterior ischemic optic neuropathy.玻璃体内注射曲安奈德治疗急性非动脉炎性前部缺血性视神经病变的疗效
Korean J Ophthalmol. 2009 Mar;23(1):59-61. doi: 10.3341/kjo.2009.23.1.59. Epub 2009 Mar 9.
4
Hypothesis: a venous etiology for nonarteritic anterior ischemic optic neuropathy.假说：非动脉炎性前部缺血性视神经病变的静脉病因
Arch Ophthalmol. 2008 Nov;126(11):1582-5. doi: 10.1001/archopht.126.11.1582.
5
Intravitreal triamcinolone acetonide injection for acute non-arteritic anterior ischaemic optic neuropathy.玻璃体内注射曲安奈德治疗急性非动脉炎性前部缺血性视神经病变。
Clin Exp Optom. 2008 Nov;91(6):561-4. doi: 10.1111/j.1444-0938.2008.00287.x.
6
Management of optic neuritis and impact of clinical trials: an international survey.视神经炎的管理及临床试验的影响：一项国际调查。
J Neurol Sci. 2009 Jan 15;276(1-2):69-74. doi: 10.1016/j.jns.2008.08.039. Epub 2008 Oct 16.
7
Etiology and treatment of macular edema.黄斑水肿的病因及治疗
Am J Ophthalmol. 2009 Jan;147(1):11-21.e1. doi: 10.1016/j.ajo.2008.07.024. Epub 2008 Sep 13.
8
Subretinal fluid from anterior ischemic optic neuropathy demonstrated by optical coherence tomography.光学相干断层扫描显示前部缺血性视神经病变的视网膜下液。
Arch Ophthalmol. 2008 Jun;126(6):812-5. doi: 10.1001/archopht.126.6.812.
9
Non-arteritic anterior ischemic optic neuropathy: role of systemic corticosteroid therapy.非动脉炎性前部缺血性视神经病变：全身糖皮质激素治疗的作用
Graefes Arch Clin Exp Ophthalmol. 2008 Jul;246(7):1029-46. doi: 10.1007/s00417-008-0805-8. Epub 2008 Apr 11.
10
Intravitreal triamcinolone for nonarteritic anterior ischemic optic neuropathy.玻璃体内注射曲安奈德治疗非动脉炎性前部缺血性视神经病变。
J Neuroophthalmol. 2008 Mar;28(1):77-8; author reply 78-9. doi: 10.1097/WNO.0b013e31816781f3.
Zotero 插件