Sohn Byung Jae, Chun Bo Young, Kwon Jung Yoon
Department of Ophthalmology, Kyungpook National University, School of Medicine, Daegu, Korea.
Korean J Ophthalmol. 2009 Mar;23(1):59-61. doi: 10.3341/kjo.2009.23.1.59. Epub 2009 Mar 9.
The purpose of this case report is to evaluate the visual outcome of an intravitreal triamcinolone acetonide injection (IVTA) as a treatment for a patient with acute nonarteritic anterior ischemic optic neuropathy (NAION). A 65-year-old male patient with severe visual loss due to acute NAION was treated with 4 mg/0.1 mL IVTA. Fundus examination and measurements of the patient's best-corrected visual acuity and visual field were performed before and after the injection at 2 weeks, 1 month, 3 months, and 6 months. The best-corrected visual acuity changed from 0.05 before the injection to 0.16 at 2 weeks, 0.3 at 1 month, and 0.4 at 3 months and at the final visit. Optic disc swelling had markedly decreased at 1 week postoperatively and disappeared at 2 weeks after the injection. The clinical course of this patient suggests that an IVTA may be effective in increasing visual acuity following an acute NAION. A large randomized controlled trial is needed to assess the efficacy of IVTA as a treatment for NAION.
本病例报告的目的是评估玻璃体内注射曲安奈德（IVTA）治疗急性非动脉炎性前部缺血性视神经病变（NAION）患者的视力预后。一名因急性NAION导致严重视力丧失的65岁男性患者接受了4mg/0.1mL的IVTA治疗。在注射前以及注射后2周、1个月、3个月和6个月对患者进行了眼底检查，并测量了最佳矫正视力和视野。最佳矫正视力从注射前的0.05提高到2周时的0.16、1个月时的0.3、3个月时以及最后一次随访时的0.4。术后1周视盘肿胀明显减轻，注射后2周消失。该患者的临床病程表明，IVTA可能对提高急性NAION后的视力有效。需要进行一项大型随机对照试验来评估IVTA治疗NAION的疗效。
