Deep Aakash, Jain Sandeep, Sharma Prabodh Chander, Verma Prabhakar, Kumar Mahesh, Dora Chander Parkash
Department of Pharmaceutical Sciences, G.V.M. College of Pharmacy, Sonepat-131001, India.
Acta Pol Pharm. 2010 May-Jun;67(3):255-9.
Seven biphenyl-4-carboxylic acid hydrazide-hydrazones have been synthesized. These hydrazone derivatives were characterized by CHN analysis, IR, and 1H NMR spectral data. All the compounds were evaluated for their in vitro antimicrobial activity against two Gram negative strains (Escherichia coli and Pseudomonas aeruginosa) and two Gram positive strains (Bacillus subtilis and Staphylococcus aureus) and fungal strain Candida albicans and Aspergillus niger All newly synthesized compounds exhibited promising results.
已合成了七种联苯 - 4 - 羧酸酰肼腙。这些腙衍生物通过CHN分析、红外光谱和¹H NMR光谱数据进行了表征。对所有化合物针对两种革兰氏阴性菌株（大肠杆菌和铜绿假单胞菌）、两种革兰氏阳性菌株（枯草芽孢杆菌和金黄色葡萄球菌）以及真菌菌株白色念珠菌和黑曲霉进行了体外抗菌活性评估。所有新合成的化合物都显示出了有前景的结果。
