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肽 - 螯合物结构对基于肽的磁共振成像造影剂代谢稳定性的影响。

Effect of Peptide-Chelate Architecture on Metabolic Stability of Peptide-based MRI Contrast Agents.

作者信息

Zhang Zhaoda, Kolodziej Andrew F, Qi Jianfeng, Nair Shrikumar A, Wang Xifang, Case April W, Greenfield Matthew T, Graham Philip B, McMurry Thomas J, Caravan Peter

机构信息

A. A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, 149 Thirteenth St, Suite 2301, Charlestown, MA 02129, USA.

出版信息

New J Chem. 2010 Feb 12;2010(34):611-616. doi: 10.1039/b9nj00787c.

DOI:10.1039/b9nj00787c
PMID:20526382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2880861/
Abstract

A strategy for preparing high relaxivity, metabolically stable peptide-based MR contrast agents is described.

摘要

本文描述了一种制备高弛豫率、代谢稳定的基于肽的磁共振造影剂的策略。

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2
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Acc Chem Res. 2009 Jul 21;42(7):851-62. doi: 10.1021/ar800220p.
3
A lysine walk to high relaxivity collagen-targeted MRI contrast agents.
Chem Rev. 2019 Jan 23;119(2):957-1057. doi: 10.1021/acs.chemrev.8b00363. Epub 2018 Oct 16.
4
Peptide-based fibrin-targeting probes for thrombus imaging.用于血栓成像的基于肽的纤维蛋白靶向探针。
Dalton Trans. 2017 Oct 31;46(42):14488-14508. doi: 10.1039/c7dt02634j.
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J Nucl Med. 2017 Dec;58(12):1991-1996. doi: 10.2967/jnumed.117.193532. Epub 2017 Jun 13.
6
MR imaging probes: design and applications.磁共振成像探针：设计与应用。
Dalton Trans. 2015 Mar 21;44(11):4804-4818. doi: 10.1039/c4dt02958e.
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A new ditopic Gd(III) complex functionalized with an adamantyl moiety as a versatile building block for the preparation of supramolecular assemblies.一种新的双齿 Gd(III) 配合物，用金刚烷部分官能化，作为制备超分子组装体的多功能构筑块。
J Biol Inorg Chem. 2014 Feb;19(2):133-43. doi: 10.1007/s00775-013-1050-0. Epub 2013 Oct 8.
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