Cui Tao, Wang Chao, He Haining, Shi Gang, Hu Lina
Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Eur J Gynaecol Oncol. 2010;31(2):209-10.
A 21-year-old woman who presented with pelvic mass, fever and cough was admitted. Ultrasonography revealed a large solid mass and serum CA125 was increased. A bilateral salpingo-oophorectomy was performed and pathological diagnosis showed Burkitt lymphoma of bilateral ovaries. Adjuvant chemotherapy was administrated after surgery. However, on the next day, the patient had an unexpectedly high fever, sigh-like breathing, dilated pupils, and died despite rescue. This is the first report on the post-treatment tumor lysis syndrome with ovarian Burkitt's lymphoma. Identifying patients at risk and initiating therapy early are essential to avoid serious complications associated with tumor lysis syndrome.
一名出现盆腔肿块、发热和咳嗽症状的21岁女性入院。超声检查发现一个大的实性肿块,血清CA125升高。进行了双侧输卵管卵巢切除术,病理诊断显示为双侧卵巢伯基特淋巴瘤。术后给予辅助化疗。然而,术后第二天,患者意外出现高热、叹息样呼吸、瞳孔散大,经抢救无效死亡。这是关于卵巢伯基特淋巴瘤治疗后肿瘤溶解综合征的首例报告。识别有风险的患者并尽早开始治疗对于避免与肿瘤溶解综合征相关的严重并发症至关重要。