Shakeel Muhammad, McCluney Neil, Li Lawrence, Newton Jonathan Ray
Department of Otolaryngology Head & Neck Surgery, University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, Scotland, UK.
J Pak Med Assoc. 2010 Jun;60(6):494-6.
Lemierre's syndrome is caused by acute oropharyngeal infection with septic secondary thrombophlebitis of the internal jugular vein and metastatic infection. Fusobacterium necrophorum is the most commonly implicated aetiological agent. The authors present the case of a healthy young man presenting with a history of general malaise and sore throat who developed septic metastatic complications in the left upper limb. He made a complete recovery after treatment with a combination of parenteral antibiotics and a multidisciplinary approach. Early ultrasound scanning of the neck and blood cultures are advocated to diagnose this potentially fatal condition. Management involves a high degree of clinical suspicion for this often 'forgotten' condition and treatment is further discussed in the article.
勒米尔综合征由急性口咽感染伴颈内静脉化脓性继发性血栓性静脉炎及转移性感染引起。坏死梭杆菌是最常见的致病因素。作者报告了一例健康年轻男性病例,该患者有全身不适和咽痛病史,随后左上肢出现化脓性转移性并发症。经肠外抗生素联合多学科方法治疗后,他完全康复。提倡早期进行颈部超声扫描和血培养以诊断这种潜在致命疾病。管理需要对这种常被“遗忘”的疾病保持高度临床怀疑,本文将进一步讨论其治疗方法。