Clinician Scientist, University of Glasgow, Reproductive and Maternal Medicine, and Division of Developmental Medicine, Glasgow Royal Infirmary, 10 Alexandra Parade, Glasgow, G31 ER, UK.
Expert Rev Pharmacoecon Outcomes Res. 2006 Oct;6(5):541-54. doi: 10.1586/14737167.6.5.541.
The hypertensive disorders of pregnancy are common and continue to be significant contributors to maternal and perinatal mortality and morbidity, both globally and in the UK. This review aims to describe the recent developments in the understanding of the pathophysiology of the disease processes, potential strategies for identification of women at high risk, and current and future therapeutic strategies for the treatment and prevention of hypertension in pregnancy. Women who experience adverse pregnancy outcomes are also at increased risk of premature cardiovascular disease, and potential therapeutic strategies to minimize their risk profile are discussed.
妊娠高血压疾病很常见，在全球范围内和英国，它仍然是导致孕产妇和围产儿死亡和发病的重要原因。本综述旨在描述对疾病过程病理生理学的最新认识，识别高危妇女的潜在策略，以及目前和未来治疗妊娠高血压的治疗和预防策略。经历不良妊娠结局的女性也有发生心血管疾病的风险增加，讨论了潜在的治疗策略来降低其风险。
