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巴西圣保罗州博图卡图市超重儿童的代谢综合征:六种诊断标准的一致性。

Metabolic syndrome in overweight children from the city of Botucatu - São Paulo State - Brazil: agreement among six diagnostic criteria.

机构信息

Uberlândia School of Medicine, Nutrition Course, Uberlândia Federal University - UFU, Uberlândia, MG, Brazil.

出版信息

Diabetol Metab Syndr. 2010 Jun 9;2(1):39. doi: 10.1186/1758-5996-2-39.

Abstract

BACKGROUND

The metabolic syndrome has been described in children; however, a standard criterion has not been established for its diagnosis. Also, few studies have been conducted to specifically observe the possible existence of agreement among the existing diagnostic criteria. The purpose of the study is to evaluate agreement concerning prevalence rates of the metabolic syndrome diagnosed by six different criteria in overweight schoolchildren in the city of Botucatu - SP -Brazil.

METHODS

This is a cross-sectional study on 128 overweight schoolchildren. Clinical examination included anthropometry, pubertal staging evaluation, and blood pressure. Triacylglycerol, glycemia, HDL-cholesterol, insulin levels, and HOMA-IR were determined. The Kappa index, the Mann-Whitney test and the chi-square test were used for statistical analysis.

RESULTS

The prevalence of the metabolic syndrome varied from 10 to 16.5% according to different diagnostic criteria. Results were similar for boys and girls and pubertal stage. Great agreement was observed among the six different diagnostic criteria for the metabolic syndrome.

CONCLUSIONS

Different diagnostic criteria, when adopted for subjects with similar demographic characteristics, generate similar and compatible prevalence. Results suggest that it is possible to adopt any of the analyzed criteria, and the choice should be according to the components available for each situation.

摘要

背景

代谢综合征在儿童中已有描述;然而,其诊断标准尚未确立。此外,很少有研究专门观察现有的诊断标准之间是否存在一致性。本研究的目的是评估在巴西博图卡图市超重学龄儿童中,用六种不同标准诊断代谢综合征的患病率是否存在一致性。

方法

这是一项对 128 名超重学龄儿童进行的横断面研究。临床检查包括人体测量学、青春期分期评估和血压。测定三酰甘油、血糖、高密度脂蛋白胆固醇、胰岛素水平和 HOMA-IR。采用 Kappa 指数、Mann-Whitney 检验和卡方检验进行统计学分析。

结果

根据不同的诊断标准,代谢综合征的患病率从 10%到 16.5%不等。男孩和女孩以及青春期阶段的结果相似。六种不同的代谢综合征诊断标准之间存在高度一致性。

结论

当采用类似的人口统计学特征的受试者时,不同的诊断标准会产生相似且一致的患病率。研究结果表明,可以采用任何一种分析标准,选择应根据每种情况可用的指标来决定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fa0/2893090/f2a5eb002102/1758-5996-2-39-1.jpg

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