Department of Operative Dentistry, Faculty of Oral and Dental Medicine, Cairo University, Egypt.
Acta Odontol Scand. 2011 Nov;69(6):395-400. doi: 10.3109/00016357.2011.572290. Epub 2011 Apr 1.
Ozone was suggested for treatment of hypersensitive dentin. The purpose of this study was to investigate the effect of ozone, with or without the use of desensitizing agents, on patency and occlusion of simulated hypersensitive dentin.
Sixty standardized dentin slabs were randomly divided into six groups: distilled water (Control), ozone treatment, fluoride desensitizer (ALLSolutions, Dentsply), oxalate desensitizer (D/Sense Crystal, Centrix), combined use of ozone/fluoride and combined use of ozone/oxalate. Ozone gas was delivered from OzonyTronX (Mymed). Specimens were evaluated using a scanning electron microscope and digital image analysis before and after treatment.
Statistical analysis using ANOVA and Mann-Whitney U-tests revealed significantly lower percentage of tubular occlusion with ozone treatment than distilled water at p ≤ 0.05. Scanning electron microscope photomicrographs of oxalate desensitizer specimens revealed a thick homogenous precipitate with significantly higher percentage of tubular occlusion than fluoride desensitizer and distilled water. Combined use of ozone/fluoride resulted in a significantly higher percentage of tubular occlusion than fluoride desensitizer alone. However, no significant difference was found between oxalate desensitizer and combined use of ozone/oxalate.
The use of ozone gas is a viable adjunct to fluoride-containing desensitizers in enhancing tubular occlusion, but is not effective with oxalate desensitizers.
臭氧被推荐用于治疗牙本质过敏。本研究的目的是研究臭氧（无论是否使用脱敏剂）对模拟牙本质过敏的通透性和闭塞的影响。
将 60 个标准化牙本质板随机分为六组：蒸馏水（对照）、臭氧处理、氟化物脱敏剂（ALLSolutions，Dentsply）、草酸盐脱敏剂（D/Sense Crystal，Centrix）、臭氧/氟化物联合使用和臭氧/草酸盐联合使用。臭氧气体由 OzonyTronX（Mymed）输送。在处理前后，使用扫描电子显微镜和数字图像分析对标本进行评估。
使用方差分析和曼-惠特尼 U 检验进行统计分析显示，与蒸馏水相比，臭氧处理后牙本质小管闭塞率显著降低（p ≤ 0.05）。草酸盐脱敏剂标本的扫描电子显微镜照片显示出一种厚厚的均匀沉淀物，与氟化物脱敏剂和蒸馏水相比，牙本质小管闭塞率显著更高。臭氧/氟化物联合使用的牙本质小管闭塞率显著高于单独使用氟化物脱敏剂。然而，草酸盐脱敏剂与臭氧/草酸盐联合使用之间没有发现显著差异。
臭氧气体的使用是增强牙本质小管闭塞的含氟脱敏剂的可行辅助手段，但与草酸盐脱敏剂无效。
