Nikischin W, Conradt A, Schröder H
Abt. Allgemeine Pädiatrie, Universitäts-Kinderklinik Kiel.
Z Geburtshilfe Perinatol. 1991 Jan-Feb;195(1):16-20.
The HELLP-syndrome is complicated by a maternal mortality of 3.5% and a perinatal mortality between 9.5 and 60%. It is a variant of severe preeclampsia which includes hemolysis, elevated liver enzymes and low platelets. It is described in the literature that neonates of mothers with HELLP-syndrome show characteristic symptoms especially thrombocytopenia, leukocytopenia and prenatal somatic dystrophy. In this retrospective investigation of 36 preterm and term infants of mothers with HELLP-syndrome we found the following results: 1. Thrombocytopenia was seen in 11% and leucocytopenia in 12% of the analysed cases. Anemia was seen in 10% of the analysed neonates. They needed transfusion of blood. The rate of prenatal somatic dystrophy was increased (58%). 2. Elevated blood pressure was observed in 29% of the neonates within the analysed interval. The time of artificial ventilation of preterm infants with maternal HELLP-syndrome was in 37% extended in comparison with infants without HELLP-syndrome in pregnancy. 3. The perinatal mortality was 8%. All observed infants during delivery and of the neonatal period in our collective survived.
HELLP综合征的孕产妇死亡率为3.5%，围产期死亡率在9.5%至60%之间。它是重度子痫前期的一种变体，包括溶血、肝酶升高和血小板减少。文献记载，患有HELLP综合征的母亲所生新生儿有特征性症状，尤其是血小板减少、白细胞减少和产前躯体发育不良。在对36例患有HELLP综合征母亲的早产和足月婴儿进行的这项回顾性研究中，我们发现了以下结果：1. 在分析的病例中，11%出现血小板减少，12%出现白细胞减少。10%的分析新生儿出现贫血。他们需要输血。产前躯体发育不良的发生率增加（58%）。2. 在分析期间，29%的新生儿血压升高。患有HELLP综合征母亲的早产婴儿人工通气时间比孕期未患HELLP综合征的婴儿延长37%。3. 围产期死亡率为8%。我们研究群体中所有观察到的分娩期和新生儿期婴儿均存活。
