Olives Casey, Pagano Marcello
Harvard School of Public Health, Boston, MA, 02115, USA.
Emerg Themes Epidemiol. 2010 Jun 9;7(1):3. doi: 10.1186/1742-7622-7-3.
Lot Quality Assurance Sampling (LQAS) applications in health have generally relied on frequentist interpretations for statistical validity. Yet health professionals often seek statements about the probability distribution of unknown parameters to answer questions of interest. The frequentist paradigm does not pretend to yield such information, although a Bayesian formulation might. This is the source of an error made in a recent paper published in this journal. Many applications lend themselves to a Bayesian treatment, and would benefit from such considerations in their design. We discuss Bayes-LQAS (B-LQAS), which allows for incorporation of prior information into the LQAS classification procedure, and thus shows how to correct the aforementioned error. Further, we pay special attention to the formulation of Bayes Operating Characteristic Curves and the use of prior information to improve survey designs. As a motivating example, we discuss the classification of Global Acute Malnutrition prevalence and draw parallels between the Bayes and classical classifications schemes. We also illustrate the impact of informative and non-informative priors on the survey design. Results indicate that using a Bayesian approach allows the incorporation of expert information and/or historical data and is thus potentially a valuable tool for making accurate and precise classifications.
批量质量保证抽样法(LQAS)在医疗卫生领域的应用通常依赖于频率学派的解释来确保统计有效性。然而,医疗卫生专业人员常常寻求关于未知参数概率分布的陈述,以回答他们感兴趣的问题。频率学派的范式并不旨在提供此类信息,而贝叶斯方法或许可以。这就是近期发表在本期刊上的一篇论文中出现错误的根源。许多应用适合采用贝叶斯方法处理,并且在设计中考虑此类方法会有所助益。我们讨论了贝叶斯 - LQAS(B - LQAS),它允许将先验信息纳入LQAS分类程序,从而展示了如何纠正上述错误。此外,我们特别关注贝叶斯操作特征曲线的构建以及如何利用先验信息改进调查设计。作为一个启发性示例,我们讨论了全球急性营养不良患病率的分类,并对比了贝叶斯分类方案和经典分类方案。我们还阐述了信息性先验和非信息性先验对调查设计的影响。结果表明,采用贝叶斯方法能够纳入专家信息和/或历史数据,因此可能是进行准确且精确分类的宝贵工具。