GeneXpert 可捕获不稳定的耐甲氧西林金黄色葡萄球菌，此类细菌容易迅速失去 mecA 基因。
GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene.
机构信息
Institute of Medical Microbiology, University of Zürich, Zurich, Switzerland.
出版信息
J Clin Microbiol. 2010 Aug;48(8):3030-2. doi: 10.1128/JCM.02113-09. Epub 2010 Jun 9.
Abstract
A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.
摘要
经 Cepheid GeneXpert 鉴定，一株对头孢西丁敏感的金黄色葡萄球菌被确认为耐甲氧西林金黄色葡萄球菌（MRSA）。该菌株在体外传代培养时极不稳定，迅速丢失 SCCmec，表明不稳定的 MRSA 最好通过基于基因扩增的方法进行检测。
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