Department of Urban Engineering, Graduate School of Engineering, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Lett Appl Microbiol. 2010 Jul;51(1):119-21. doi: 10.1111/j.1472-765X.2010.02869.x. Epub 2010 May 14.
To evaluate the reduction of human norovirus (HuNoV) by chlorine disinfection under typical drinking water treatment conditions.
HuNoV, murine norovirus (MNV) and poliovirus type 1 (PV1) were inoculated into treated water before chlorination, collected from a drinking water treatment plant, and bench-scale free chlorine disinfection experiments were performed for two initial free chlorine concentrations, 0.1 and 0.5 mg l(-1). Inactivation of MNV reached more than 4 log(10) after 120 and 0.5 min contact time to chlorine at the initial free chlorine concentrations of 0.1 and 0.5 mg l(-1), respectively.
MNV was inactivated faster than PV1, and there was no significant difference in the viral RNA reduction rate between HuNoV and MNV. The results suggest that appropriate water treatment process with chlorination can manage the risk of HuNoV infection via drinking water supply systems.
The data obtained in this study would be useful for assessing or managing the risk of HuNoV infections from drinking water exposure.
评估在典型饮用水处理条件下氯消毒对人类诺如病毒（HuNoV）的减少效果。
在氯化前将 HuNoV、鼠诺如病毒（MNV）和脊髓灰质炎病毒 1 型（PV1）接种到处理水中，从饮用水处理厂采集，并进行了两个初始游离氯浓度（0.1 和 0.5mg/L）的现场规模自由氯消毒实验。在初始游离氯浓度为 0.1 和 0.5mg/L 时，MNV 在 120 和 0.5 分钟接触时间后分别达到超过 4 个对数减少（10）。
MNV 的失活速度快于 PV1，且 HuNoV 和 MNV 的病毒 RNA 减少率无显著差异。结果表明，通过饮用水供应系统，适当的氯化水处理工艺可以控制 HuNoV 感染的风险。
本研究获得的数据将有助于评估或管理因饮用受污染的水而感染 HuNoV 的风险。
