Department of Psychology, Center for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, USA.
Exp Clin Psychopharmacol. 2010 Jun;18(3):214-20. doi: 10.1037/a0019635.
Researchers have identified the association between the use of cocaine and sexual behavior as an important risk factor for HIV infection and have attempted to elucidate the nature of this association. Several lines of research have suggested that facilitation of sexual behavior during intoxication with cocaine may be because of the direct pharmacological effects of the drug (e.g., increase in sexual desire), whereas others have pointed to the importance of factors related to the context of drug use (e.g., opportunities for sexual behavior, expectations about the effects of the drug, social norms). The present study explored the perceived effects of cocaine and heroin on sexual behavior, as well as the social context of drug use as a function of drug type (cocaine vs. heroin), among 46 inner-city drug users who reported a history of regular use of both crack cocaine and heroin. Results indicated that compared to heroin, cocaine had deleterious effects on participants' perceived sexual desire and performance. Despite such deleterious effects on sexual behavior, cocaine was more frequently used with an intimate partner than heroin. Furthermore, participants did not differ in the extent to which they used the two drugs in other social contexts (e.g., with friends, family, or neighbors). These preliminary results suggest that the relationship between cocaine and sexual behavior, especially among long-term cocaine users, may be facilitated by opportunities for sex that exist in the context of cocaine use, rather than by the pharmacological effects of the drug.
研究人员已经确定,可卡因的使用与性行为之间的关联是 HIV 感染的一个重要风险因素,并试图阐明这种关联的性质。有几条研究线索表明,在可卡因中毒期间促进性行为可能是由于药物的直接药理作用(例如,性欲增加),而另一些则指出与药物使用背景相关的因素的重要性(例如,性行为的机会、对药物作用的期望、社会规范)。本研究探讨了可卡因和海洛因对性行为的感知影响,以及作为药物类型(可卡因与海洛因)功能的药物使用的社会背景,在 46 名报告有定期使用可卡因和海洛因的城市内吸毒者中进行。结果表明,与海洛因相比,可卡因对参与者的感知性欲和表现产生了有害影响。尽管可卡因对性行为有如此有害的影响,但可卡因与亲密伴侣一起使用的频率却高于海洛因。此外,参与者在两种药物在其他社会背景下(例如与朋友、家人或邻居)的使用程度上没有差异。这些初步结果表明,可卡因与性行为之间的关系,尤其是在长期可卡因使用者中,可能是由于可卡因使用背景下存在的性行为机会而不是药物的药理作用促成的。