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爱情是一种上瘾的激情障碍吗?

Is love passion an addictive disorder?

机构信息

Inserm, U, Paris, France.

出版信息

Am J Drug Alcohol Abuse. 2010 Sep;36(5):261-7. doi: 10.3109/00952990.2010.495183.

Abstract

AIMS

Inquiry regarding the relationship between passionate love and addiction has long been a topic of intense debate. Recent advances in neurobiology now allow for an examination between these two states.

METHODS

After describing the clinical distinctions between "love passion," "love addiction," and "sex addiction," we compare clinical, neuropsychological, neurobiological, and neuroimaging data on love, passion, pathological gambling (PG) and substance dependence.

RESULTS

There are no recognized definitions or diagnostic criteria for "love addiction," but its phenomenology has some similarities to substance dependence: euphoria and unrestrained desire in the presence of the love object or associated stimuli (drug intoxication); negative mood, anhedonia, and sleep disturbance when separated from the love object (drug withdrawal); focussed attention on and intrusive thoughts about the love object; and maladaptive or problematic patterns of behavior (love relation) leading to clinically significant impairment or distress, with pursuit despite knowledge of adverse consequences. Limited animal and human studies suggest that brain regions (e.g., insula, anterior cingulated [ACC], orbitofrontal [OFC]) and neurotransmitters (dopamine) that mediate substance dependence may also be involved with love addiction (as for PG). Ocytocin (OT), which is implicated in social attachment and mating behavior, may also be involved in substance dependence. There are no data on the epidemiology, genetics, co-morbidity, or treatment of love addiction.

CONCLUSION

There are currently insufficient data to place some cases of "love passion" within a clinical disorder, such as "love addiction," in an official diagnostic nomenclature or to firmly classify it as a behavioral addiction or disorder of impulse control. Further clinical and scientific studies are needed to improve our understanding and treatment of this condition. For these studies, we propose new criteria for evaluating addiction to love.

摘要

目的

热衷于探究激情之爱与成瘾之间的关系由来已久。神经生物学的最新进展使我们能够对这两种状态进行检验。

方法

在描述了“爱情激情”、“爱情成瘾”和“性成瘾”之间的临床区别后,我们比较了关于爱情、激情、病态赌博(PG)和物质依赖的临床、神经心理学、神经生物学和神经影像学数据。

结果

目前还没有“爱情成瘾”的公认定义或诊断标准,但它的表现与物质依赖有一些相似之处:在有爱的对象或相关刺激物存在时出现欣快和无法抑制的欲望(药物中毒);与爱的对象分离时出现负面情绪、快感缺失和睡眠障碍(药物戒断);对爱的对象的注意力集中和侵入性思维;以及导致临床显著损害或痛苦的适应不良或有问题的行为模式(恋爱关系),尽管明知有不良后果仍继续追求。有限的动物和人类研究表明,介导物质依赖的大脑区域(例如,岛叶、前扣带回[ACC]、眶额[OFC])和神经递质(多巴胺)也可能与爱情成瘾(如 PG)有关。催产素(OT)参与社会依恋和交配行为,也可能与物质依赖有关。目前尚无关于爱情成瘾的流行病学、遗传学、共病或治疗的数据。

结论

目前,将某些情况下的“爱情激情”置于临床障碍(如“爱情成瘾”)中,或将其明确归类为行为成瘾或冲动控制障碍的相关数据还不够充分。需要进一步的临床和科学研究来增进我们对这种情况的理解和治疗。为此,我们提出了评估对爱情成瘾的新标准。

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