Department of Electrophysics, National Chiao Tung University, Taiwan, China.
Opt Lett. 2010 Jun 15;35(12):1959-61. doi: 10.1364/OL.35.001959.
We develop light-driven optoelectronic tweezers based on the organic photoconductive material titanium oxide phthalocyanine. These tweezers function based on negative dielectrophoresis (nDEP). The dynamic manipulation of a single microparticle and cell patterning are demonstrated by using this light-driven optoelectronic DEP chip. The adaptive light patterns that drive the optoelectronic DEP onchip are designed by using Flash software to approach appropriate dynamic manipulation. This is also the first reported demonstration, to the best of our knowledge, for successfully patterning such delicate cells from human hepatocellular liver carcinoma cell line HepG2 by using any optoelectronic tweezers.
我们基于有机光电导材料钛氧化物酞菁开发了光驱动的光电镊子。这些镊子基于负介电泳（nDEP）原理工作。通过使用这种光驱动的光电 DEP 芯片，演示了对单个微粒子的动态操纵和细胞图案化。使用 Flash 软件设计用于驱动光电子 DEP 的自适应光图案，以实现适当的动态操纵。据我们所知，这也是首次成功使用任何光镊对来自人肝癌细胞系 HepG2 的如此脆弱的细胞进行图案化的报道。
