Department of Dermatology, Charles Nicolle Hospital, Boulevard 9 Avril Tunis, Tunis, Tunisia 1006.
Dermatol Ther (Heidelb). 2011 Sep;1(1):15-9. doi: 10.1007/s13555-011-0004-0. Epub 2011 May 20.
Disseminated superficial actinic porokeratosis (DSAP) is the most common form of porokeratosis. A case of late-onset DSAP is reported with an uncommon presentation in an elderly patient.
An 80-year-old woman, with diabetes mellitus treated with metformin, and hypertension treated with metoprolol and captopril, presented with multiple 2 mm-to-7 cm brown patches, for 5 years. The patches were often confluent with an atrophic center and a well-demarcated keratotic border located on the thighs, lower legs, and feet.
Histological examination of a cutaneous biopsy showed the presence of rare cornoid lamellae, confirming the clinical diagnosis of DSAP.
In this report, the atypical presentation of DSAP is discussed in this elderly patient and also the possible triggering factors at this age.
播散性浅表性光线性汗孔角化症（DSAP）是汗孔角化症中最常见的一种类型。本文报道了一例罕见的迟发性 DSAP 病例，其在老年患者中表现为不常见的临床表现。
一位 80 岁的女性，患有糖尿病，接受二甲双胍治疗，患有高血压，接受美托洛尔和卡托普利治疗，出现多发性 2 毫米至 7 厘米的棕色斑块，持续 5 年。这些斑块经常融合，具有萎缩中心和位于大腿、小腿和足部的边界清楚的角化边界。
皮肤活检的组织学检查显示罕见的Cornoid 板层存在，证实了 DSAP 的临床诊断。
在本报告中，讨论了这位老年患者中 DSAP 的非典型表现以及这个年龄可能的触发因素。
