Filimonov V I, Nedospasov V O, Stepanova N V
Fiziol Zh (1978). 1991 Mar-Apr;37(2):12-8.
The dynamics of erythropoiesis during the bone restoration and under the conditions of perturbing influence: fracture and hemolytic anemia have been studied in the experiment. It is found that under the conditions of callus formation the process of proliferation and differentiation of red cells in the bone marrow is inhibited. The observed effect of erythropoiesis inhibition may be caused by the intercellular interaction of regenerating tissues in their "struggle" for microphages, which, while being the centre of the erythroid insula secure the maturation of erythroid precursors, and at the same time they can take part in the bone formation process.
在实验中研究了骨修复过程中以及在干扰影响条件下(骨折和溶血性贫血)红细胞生成的动力学。发现骨痂形成条件下骨髓中红细胞的增殖和分化过程受到抑制。观察到的红细胞生成抑制作用可能是由于再生组织在争夺巨噬细胞的“斗争”中的细胞间相互作用所致,巨噬细胞是红系岛的中心,确保红系前体细胞的成熟,同时它们也可参与骨形成过程。