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漆树和五倍子——从民间传说到现代证据:综述。

Rhus chinensis and Galla Chinensis--folklore to modern evidence: review.

机构信息

School of Food Science and Technology, Jiangnan University, Food Safety and Quality Control Laboratory, Wuxi, 214122, Jiangsu Province, P.R. China.

出版信息

Phytother Res. 2010 Dec;24(12):1739-47. doi: 10.1002/ptr.3215.

DOI:10.1002/ptr.3215
PMID:20564459
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7167973/
Abstract

The species Rhus chinensis Mill. (Anacardiaceae) is an important representative of the genus Rhus, which contains over 250 individual species found in temperate and tropical regions worldwide. Rhus chinensis has long been used by folk medicine practitioners in Asia. Leaves, roots, stem, bark, fruit and particularly the galls on Rhus chinensis leaves, Galla chinensis, are recognized to have preventative and therapeutic effects on different ailments (such as diarrhea, dysentery, rectal and intestinal cancer, diabetes mellitus, sepsis, oral diseases and inflammation). However, it is critical to separate evidence from anecdote. Fortunately, recent scientific research has revealed that Rhus chinensis compounds possess strong antiviral, antibacterial, anticancer, hepatoprotective, antidiarrheal and antioxidant activities. Moreover, compounds isolated from the stem of Rhus chinensis significantly suppressed HIV-1 activity in vitro. Compounds from this plant were also found to inhibit enamel demineralization in vitro and enhance remineralization of dental enamel with fluoride. This review highlights claims from traditional and tribal medicinal lore and makes a contemporary summary of phytochemical, biological and pharmacological findings on this plant material. It aims to show that the pharmaceutical potential of this plant deserves closer attention.

摘要

植物漆树(漆树科)是漆树属的重要代表之一,该属约有 250 种,分布于全球的温带和热带地区。亚洲民间医学从业者长期以来一直使用漆树属植物。漆树的叶子、根、茎、树皮、果实,特别是叶子上的虫瘿,被认为对不同的疾病(如腹泻、痢疾、直肠癌和结肠癌、糖尿病、败血症、口腔疾病和炎症)具有预防和治疗作用。然而,将证据与传闻区分开来至关重要。幸运的是,最近的科学研究表明,漆树化合物具有很强的抗病毒、抗菌、抗癌、保肝、抗腹泻和抗氧化活性。此外,从漆树茎中分离得到的化合物在体外显著抑制了 HIV-1 的活性。还发现这种植物的化合物能抑制体外牙釉质脱矿,并能增强氟化物对牙釉质的再矿化作用。本综述重点介绍了传统和部落医学传说中的说法,并对该植物材料的植物化学、生物学和药理学研究结果进行了现代综述。目的是表明该植物的药用潜力值得进一步关注。

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Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose.五倍子酰葡萄糖的抗癌、抗糖尿病及其他药理和生物学活性
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Antibacterial activity of methyl gallate isolated from Galla Rhois or carvacrol combined with nalidixic acid against nalidixic acid resistant bacteria.从五倍子中分离得到的没食子酸甲酯或香芹酚与萘啶酸联合对萘啶酸耐药菌的抗菌活性。
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Penta-O-galloyl-beta-D-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression.五-O-没食子酰基-β-D-葡萄糖通过转录抑制表皮生长因子诱导的基质金属蛋白酶-9表达来抑制前列腺癌骨转移。
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