Hurd E R
J Rheumatol. 1978 Spring;5(1):26-32.
The spleens from two patients with Felty's syndrome and the bone marrow from one patient with Felty's syndrome were examined for the presence of intracytoplasmic inclusions in neutrophils when stained with antibodies to IgG, IgM, IgA, and betalc. Four normal spleens from trauma patients were similarly examined. In both spleens and the bone marrow from the Felty patients, large inclusions were noted. In none of the four normal spleens were large inclusions present. These studies suggest that phagocytosis of immune complexes by neutrophils in Felty patients may induce sequestration of these cells in the spleen and bone marrow.
对两名费尔蒂综合征患者的脾脏以及一名费尔蒂综合征患者的骨髓进行检查，以观察当中性粒细胞用抗IgG、IgM、IgA和βc抗体染色时胞质内包含物的情况。对四名创伤患者的正常脾脏也进行了类似检查。在费尔蒂综合征患者的脾脏和骨髓中均发现了大的包含物。在四个正常脾脏中均未发现大的包含物。这些研究表明，费尔蒂综合征患者中性粒细胞对免疫复合物的吞噬作用可能会导致这些细胞在脾脏和骨髓中滞留。
