Department of Cancer and Surgery, Centre of Oncology, Oslo University Hospital, Ullevål, Norway.
Contact Dermatitis. 2010 Mar;62(3):170-6. doi: 10.1111/j.1600-0536.2009.01679.x.
Hand eczema risk factors are potentially associated with lifestyle, and changes in lifestyle may influence the prevalence of this condition.
To report potential lifestyle risk factors and their association with hand eczema.
PATIENTS/MATERIALS/METHODS: Cross-sectional questionnaire survey and standard patch test among Swedish upper secondary school children. The participation rate was 81% (6095/7543) for the questionnaire and 59% (4439/7543) for the test.
Girls reported piercing (84% versus 18%), tattooing (6% versus 3%), smoking (24% versus 16%) and vegetarianism (21% versus 7%) significantly more often than boys. Girls had significantly more hand eczema (7% versus 4%) than boys. Besides female sex (OR 2.0), allergic rhinitis (OR 1.8), flexural eczema (OR 4.5), and positive nickel test (OR 1.7) were significant risk factors in multivariate analysis. Piercing entailed a decreased risk (OR 0.6). Other lifestyle practices had no association with hand eczema. Vegetarian diet and dental braces which potentially increase oral nickel exposure were not associated with hand eczema prevalence in nickel sensitized individuals.
The studied lifestyle practices were more prevalent in girls. Smoking, tattooing, and diet were not associated with the occurrence of hand eczema.
手部湿疹的危险因素可能与生活方式有关，生活方式的改变可能会影响这种疾病的流行率。
报告潜在的生活方式危险因素及其与手部湿疹的关系。
患者/材料/方法：对瑞典中学的学生进行横断面问卷调查和标准斑贴试验。问卷的参与率为 81%（6095/7543），而测试的参与率为 59%（4439/7543）。
女孩比男孩更常报告穿孔（84%比 18%）、纹身（6%比 3%）、吸烟（24%比 16%）和素食主义（21%比 7%）。女孩的手部湿疹（7%比 4%）明显多于男孩。除了女性（OR 2.0）、过敏性鼻炎（OR 1.8）、屈侧湿疹（OR 4.5）和镍阳性测试（OR 1.7）外，多变量分析还表明其他危险因素包括阳性镍测试（OR 1.7）。穿孔会降低风险（OR 0.6）。其他生活方式与手部湿疹无关。素食和牙箍可能会增加口腔镍暴露，但在镍敏感个体中与手部湿疹的患病率无关。
研究中的生活方式在女孩中更为普遍。吸烟、纹身和饮食与手部湿疹的发生无关。
