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葡萄糖的混合酸发酵作为气肿性尿路感染的一种机制。

Mixed acid fermentation of glucose as a mechanism of emphysematous urinary tract infection.

作者信息

Huang J J, Chen K W, Ruaan M K

机构信息

Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan, Republic of China.

出版信息

J Urol. 1991 Jul;146(1):148-51. doi: 10.1016/s0022-5347(17)37736-4.

Abstract

Emphysematous pyelonephritis is a severe necrotizing infection that usually occurs in patients with diabetes mellitus or obstructive uropathy. Although glucose fermentation has been considered as the main cause of gas production the actual mechanism remains controversial. Compositions of gas samples from 2 patients with emphysematous pyelonephritis recently encountered were analyzed, and showed 15% hydrogen, 4.8% carbon dioxide, 60% nitrogen, 6.7% oxygen and some unknown gases in case 1, and 3.4% hydrogen, 22% carbon dioxide, 66% nitrogen and 9.8% oxygen in case 2. These results tend to implicate mixed acid fermentation of glucose as the pathway by which emphysematous urinary tract infections develop.

摘要

气肿性肾盂肾炎是一种严重的坏死性感染,通常发生于糖尿病或梗阻性尿路病患者。尽管葡萄糖发酵被认为是产气的主要原因,但实际机制仍存在争议。对最近遇到的2例气肿性肾盂肾炎患者的气体样本成分进行了分析,结果显示,病例1的气体样本中氢气占15%、二氧化碳占4.8%、氮气占60%、氧气占6.7%,还有一些未知气体;病例2的气体样本中氢气占3.4%、二氧化碳占22%、氮气占66%、氧气占9.8%。这些结果倾向于表明,葡萄糖的混合酸发酵是气肿性尿路感染发生发展的途径。

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