流感：曾今及未来的大流行疾病。
Influenza: the once and future pandemic.
机构信息
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 33 North Dr., Rm. 3E19A.2, MSC 3203, Bethesda, MD 20892-3203, USA.
出版信息
Public Health Rep. 2010 Apr;125 Suppl 3(Suppl 3):16-26.
Abstract
Influenza A viruses infect large numbers of warm-blooded animals, including wild birds, domestic birds, pigs, horses, and humans. Influenza viruses can switch hosts to form new lineages in novel hosts. The most significant of these events is the emergence of antigenically novel influenza A viruses in humans, leading to pandemics. Influenza pandemics have been reported for at least 500 years, with inter-pandemic intervals averaging approximately 40 years.
摘要
甲型流感病毒感染大量的温血动物，包括野生鸟类、家禽、猪、马和人类。流感病毒可以在新宿主中发生宿主转换，形成新的谱系。其中最重要的事件是抗原性新型甲型流感病毒在人类中的出现，导致大流行。至少在 500 年来，一直有流感大流行的报告，大流行之间的平均间隔约为 40 年。
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