Ellefson R D, Elveback L R, Hodgson P A, Weidman W H
Mayo Clin Proc. 1978 May;53(5):307-20.
Cholesterol and triglyceride levels in whole sera and in the major lipoprotein fractions are presented for 2,421 children and youths in Rochester, Minnesota, ranging in age from 6 to 18 years. This cross-sectional study revealed subtle changes associated with puberty and the occurrence of certain additional sex-specific changes related to age. Hyperlipoproteinemia was detected in 101 youngsters; those cases exemplified types IIa (61 cases), IIb (5 cases), III (5 cases), and IV (30 cases). One case of type V hyperlipoproteinemia was observed in a second and comparable population sample of 1,245 young persons.
本文呈现了明尼苏达州罗切斯特市2421名年龄在6至18岁的儿童和青少年的全血清以及主要脂蛋白组分中的胆固醇和甘油三酯水平。这项横断面研究揭示了与青春期相关的细微变化以及某些与年龄相关的额外性别特异性变化。在101名青少年中检测到了高脂蛋白血症;这些病例分别为IIa型(61例)、IIb型(5例)、III型(5例)和IV型(30例)。在另一组1245名年轻人的可比人群样本中观察到1例V型高脂蛋白血症。