Widhalm K, Strobl W
Eur J Pediatr. 1979 Oct;132(2):125-30. doi: 10.1007/BF00447380.
From 108 healthy 13 years old school children who took part on a longitudinal study in regard to serum lipids and lipoproteins 64 with normal body weight were examined. Lipoproteins were estimated by means of preparative ultracentrifuge and polyanionprecipitation (Heparin and Manganese-chloride) according to the Lipid Research Clinics Methods, NIH, Bethesda. Mean values and S.D. were calculated as: Total cholesterol: 155 +/- 29, 150 +/- 35 mg/dl; LDL-cholesterol 98 +/- 21 and 96 +/- 34 mg/dl; HDL-cholesterol 44 +/- 13 and 44 +/- 13 mg/dl for males and females respectively. The few data from the literature showing wide variations in LDL- and HDL-cholesterol concentrations are compared with our results; methodological considerations indicate that for further epidemiological studies concerning the possible risk factors for premature atherosclerosis standaradized laboratory tests should be provided.
在108名参与血清脂质和脂蛋白纵向研究的13岁健康学童中，对64名体重正常的儿童进行了检查。根据美国国立卫生研究院贝塞斯达脂质研究诊所的方法，通过制备性超速离心和聚阴离子沉淀法（肝素和氯化锰）对脂蛋白进行评估。均值和标准差计算如下：总胆固醇：男性为155±29mg/dl，女性为150±35mg/dl；低密度脂蛋白胆固醇：男性为98±21mg/dl，女性为96±34mg/dl；高密度脂蛋白胆固醇：男性和女性均为44±13mg/dl。将文献中显示低密度脂蛋白和高密度脂蛋白胆固醇浓度存在广泛差异的少数数据与我们的结果进行了比较；方法学上的考虑表明，对于进一步关于早发性动脉粥样硬化可能危险因素的流行病学研究，应提供标准化的实验室检测。
