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[短筒兔耳草的化学成分]

[Chemical constituents from Lagotis brevituba].

作者信息

Chi Feng, Deng Jun, Wang Yanhan

机构信息

College of Pharmaceutical Sciences, Southwest University, Chongqing 400716, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2010 Apr;35(7):869-71. doi: 10.4268/cjcmm20100714.

DOI:10.4268/cjcmm20100714
PMID:20575388
Abstract

OBJECTIVE

To study on the chemical consitituents of Lagotis brevituba.

METHOD

The chemical consitituents were isolated by silica gel column chromatography, polyamide column chromatography and semi-preparative HPLC, and their structures were identified by spectroscopic methods.

RESULT

Eight compounds were isolated and they were identified as beta-sitosterol (1), succinic acid (2), luteolin-7-O-beta-D-glucoside (3), uracil (4), apigenin (5), chrysoeriol (6), chrysoeriol-7-O-beta-D-glucoside (7), and apigenin-7-O-beta-D-glucoside (8).

CONCLUSION

Compound 4-8 were isolated from L. brevituba for the first time, and among them, compound 7 and 8 were isolated from genus Lagotis for the first time.

摘要

目的

研究短筒兔耳草的化学成分。

方法

采用硅胶柱色谱、聚酰胺柱色谱和半制备高效液相色谱法分离化学成分,并通过光谱方法鉴定其结构。

结果

分离得到8个化合物,分别鉴定为β-谷甾醇(1)、琥珀酸(2)、木犀草素-7-O-β-D-葡萄糖苷(3)、尿嘧啶(4)、芹菜素(5)、 Chrysoeriol(6)、 Chrysoeriol-7-O-β-D-葡萄糖苷(7)和芹菜素-7-O-β-D-葡萄糖苷(8)。

结论

化合物4-8首次从短筒兔耳草中分离得到,其中化合物7和8首次从兔耳草属植物中分离得到。

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