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苏格兰 2009 年甲型 H1N1 流感大流行病毒:冬季疫情后,2010 年春季的地域差异免疫情况。

2009 pandemic influenza A(H1N1) virus in Scotland: geographically variable immunity in Spring 2010, following the winter outbreak.

机构信息

West of Scotland Specialist Virology Centre, Glasgow, Scotland.

出版信息

Euro Surveill. 2010 Jun 17;15(24):19590.

PMID:20576237
Abstract

We determined the age- and location-specific seroprevalence of antibodies against 2009 pandemic influenza A(H1N1) virus in Scotland following the first two waves of infection. Serum samples collected following the winter outbreak were analysed by microneutralisation assay. The proportion of positive sera varied significantly between cities and, in the case of Inverness, between age groups (with younger adults more likely to be positive than older individuals). This study demonstrates that older people are no longer more likely to have antibodies against the virus than younger adults.

摘要

我们在苏格兰经历了前两波感染后,确定了针对 2009 年甲型 H1N1 流感病毒的抗体在年龄和地理位置上的血清流行率。通过微量中和试验分析了冬季疫情爆发后采集的血清样本。不同城市之间血清阳性率差异显著,而在因弗内斯,这种差异还存在于不同年龄组之间(年轻人比老年人更有可能呈阳性)。本研究表明,老年人对该病毒的抗体水平不再比年轻人更高。

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