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Membrane leakiness after viral infection and a new approach to the development of antiviral agents.

作者信息

Carrasco L

出版信息

Nature. 1978 Apr 20;272(5655):694-9. doi: 10.1038/272694a0.

DOI:10.1038/272694a0
PMID:205795
Abstract

Viral development induces changes in the permeability properties of the plasma membrane of the host cell. Here it is shown that, because of this leakiness, inhibitors of protein synthesis normally impermeable to uninfected cells are able to enter infected cells and thereby specifically inhibit viral protein synthesis.

摘要

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