对麻黄属植物 Nebrodensis 的药理学活性的研究。

Pharmacological activities on Ephedra nebrodensis Tineo.

机构信息

CoSMeSe, Department of Botanical Sciences, University of Cagliari, Italy.

出版信息

Nat Prod Res. 2010 Jul;24(12):1115-24. doi: 10.1080/14786410802680902.

PMID:20582807

Abstract

As a part of our endeavour to screen Mediterranean medicinal plants for various pharmacological activities, we evaluated antihistaminic, adaptogenic, anti-inflammatory, antinociceptive, hypotensive and locomotor properties, and antioxidant potential of Ephedra nebrodensis. (1)H-NMR spectroscopy was carried out to identify the plant metabolites, which confirmed the presence of ephedrinic skeleton alkaloids. The ethanol : acetone (1 : 1) extract exhibited dose-related antihistaminic, anti-inflammatory, antinociceptive, hypotensive, antioxidant and locomotor stimulant activity. The plant bears potential for further studies.

摘要

作为我们筛选地中海药用植物进行各种药理活性研究的一部分，我们评估了 Ephedra nebrodensis 的抗组胺、适应原、抗炎、镇痛、降压和运动活性以及抗氧化潜力。（1）H-NMR 光谱学用于鉴定植物代谢物，证实了麻黄素骨架生物碱的存在。乙醇：丙酮（1：1）提取物表现出与剂量相关的抗组胺、抗炎、镇痛、降压、抗氧化和运动刺激活性。该植物具有进一步研究的潜力。