Afroundeh R, Siahkouhian M, Khalili A
Department of Physical Education and Sport Science, University of Mohaghegh Ardabili, Ardabil, Iran.
J Sports Med Phys Fitness. 2010 Jun;50(2):182-8.
The aim of this study was to investigate muscle damage and inflammatory response following eccentric exercise as well as the effect of carbohydrate supplement on these responses in untrained men.
Eighteen healthy untrained men were randomly allocated into two carbohydrate (age 21/33+/-0/7 years) and placebo (age 20/66+/-1/22 years) groups. Forty-five repetitions of eccentric elbow flexion were performed with 90% of one maximum repetition by each subject. The exercises were done as three sets of 15 repetitions with 3 minutes rest between sets. Venous blood samples were obtained at pre-exercise, immediately, 8h, and 24h after exercise. Subjects consumed a 6% carbohydrate or placebo drink immediately following the exercise session, every hour, for 10 hours.
CK activities and IL-6 levels were significantly greater than per-exercise in immediately, 8 h and 24 h after exercise in both groups (P<0.05). No significant increases was observed in CRP levels immediately, 8 h and 24 h after exercise versus baseline, in both groups (P>0.05), but in 8 h versus immediately after exercise, the augmentation in the carbohydrate group was significant(P<0.05). Blood glucose increased significantly 8 h after exercise versus baseline in both groups (P<0.05). There was significant difference in serum IL-6 between two groups in 8 h and 24 h after exercise (P<0.05) and it was greater in carbohydrate group. There was no significant difference in serum CK, CRP, and glucose between two groups (P>0.05).
According to results, carbohydrate increased the inflammatory (IL-6) response following resistance exercise, but had no effects on CRP and CK.
本研究旨在调查未经训练的男性进行离心运动后的肌肉损伤和炎症反应，以及碳水化合物补充对这些反应的影响。
18名健康的未经训练的男性被随机分为碳水化合物组（年龄21/33±0/7岁）和安慰剂组（年龄20/66±1/22岁）。每位受试者以一次最大重复量的90%进行45次离心式屈肘动作。练习分为三组，每组15次，组间休息3分钟。在运动前、运动后即刻、8小时和24小时采集静脉血样。运动后，受试者每小时饮用一次6%的碳水化合物饮料或安慰剂饮料，共饮用10小时。
两组在运动后即刻、8小时和24小时的肌酸激酶（CK）活性和白细胞介素-6（IL-6）水平均显著高于运动前（P<0.05）。两组在运动后即刻、8小时和24小时的C反应蛋白（CRP）水平与基线相比均无显著升高（P>0.05），但在运动后8小时与即刻相比，碳水化合物组的升高具有显著性（P<0.05）。两组在运动后8小时的血糖水平均显著高于基线（P<0.05）。运动后8小时和24小时两组血清IL-6水平存在显著差异（P<0.05），碳水化合物组更高。两组血清CK、CRP和血糖水平无显著差异（P>0.05）。
根据结果，碳水化合物增加了抗阻运动后的炎症（IL-6）反应，但对CRP和CK无影响。
