Miles Mary P, Pearson Sherri D, Andring Jan M, Kidd Jessy R, Volpe Stella L
Dept. of Health and Human Development, Montana State University, Bozeman, MT 59717, USA.
Int J Sport Nutr Exerc Metab. 2007 Dec;17(6):507-20. doi: 10.1123/ijsnem.17.6.507.
The purpose of this investigation was to determine whether carbohydrate supplementation during the first 2 d postexercise recovery influenced the inflammation (IL-6, C-reactive protein [CRP], and cortisol) and muscle-damage responses. Eight participants performed a high-force eccentric elbow-flexion exercise to induce muscle soreness and inflammation and then consumed carbohydrate (0.25 g.kg(-1).h(-1)) or an equal volume of placebo during hours 0-12 and 24-36 postexercise in a double-blind, crossover protocol. Muscle soreness; midbrachial arm circumference; blood glucose, IL-6, CRP, cortisol, and creatine-kinase (CK) activity; and maximal force production were measured preexercise and 4, 8, 12, 24, 48, and 120 h postexercise. Plasma IL-6 increased, F(5) = 5.27, P < 0.05, 8 h postexercise, with no difference between carbohydrate and placebo conditions. Changes in muscle soreness, arm circumference, strength, and serum CK activity were consistent with small amounts of muscle damage and did not differ between conditions. The authors conclude that carbohydrate supplementation during recovery from soreness-inducing exercise does not influence the delayed IL-6 response temporally linked to inflammation or indications of muscle damage. Thus, increased carbohydrate consumption at levels consistent with recommendations for replenishing glycogen stores does not impair or promote the immune and muscle responses.
本研究的目的是确定运动后恢复的头2天补充碳水化合物是否会影响炎症反应（白细胞介素-6、C反应蛋白[CRP]和皮质醇）以及肌肉损伤反应。8名参与者进行了高强度离心式屈肘运动以诱发肌肉酸痛和炎症，然后在运动后的0至12小时以及24至36小时内，按照双盲、交叉试验方案，摄入碳水化合物（0.25 g·kg⁻¹·h⁻¹）或等量的安慰剂。在运动前以及运动后4、8、12、24、48和120小时测量肌肉酸痛、肱中臂围、血糖、白细胞介素-6、CRP、皮质醇和肌酸激酶（CK）活性，以及最大力量产生情况。运动后8小时，血浆白细胞介素-6升高，F(5)=5.27，P<0.05，碳水化合物组和安慰剂组之间无差异。肌肉酸痛、臂围、力量和血清CK活性的变化与少量肌肉损伤一致，且两组之间无差异。作者得出结论，在诱发酸痛的运动恢复期间补充碳水化合物不会影响与炎症或肌肉损伤迹象暂时相关的延迟白细胞介素-6反应。因此，按照补充糖原储备的建议水平增加碳水化合物摄入量不会损害或促进免疫和肌肉反应。
